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- 2024
-
Mark
Real-time monitoring of gradient chromatography using dual Kalman-filters
(
- Contribution to journal › Article
-
Mark
Automatic procedure for modelling, calibration, and optimization of a three-component chromatographic separation
(
- Contribution to journal › Article
-
Mark
Continuous downstream processing
(
- Contribution to journal › Article
-
Mark
Mechanistic modeling of empty-full separation in recombinant adeno-associated virus production using anion-exchange membrane chromatography
(
- Contribution to journal › Article
-
Mark
Accelerating vaccine manufacturing development through model-based approaches : current advances and future opportunities
(
- Contribution to journal › Scientific review
- 2023
-
Mark
Methodology for fast development of digital solutions in integrated continuous downstream processing
2023) In Biotechnology and Bioengineering(
- Contribution to journal › Article
-
Mark
Automated quality analysis in continuous downstream processes for small-scale applications
(
- Contribution to journal › Article
-
Mark
An automated buffer management system for small-scale continuous downstream bioprocessing
(
- Contribution to journal › Article
-
Mark
Real-time detection of mAb aggregates in an integrated downstream process
(
- Contribution to journal › Article
- 2022
-
Mark
Binary separation control in preparative gradient chromatography using iterative learning control
(
- Contribution to journal › Article
-
Mark
Design of an integrated continuous downstream process for acid-sensitive monoclonal antibodies based on a calcium-dependent Protein A ligand
(
- Contribution to journal › Article
-
Mark
Smart platform for development of small-scale integrated continuous downstream processes
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Integrated continuous biomanufacturing on pilot scale for acid-sensitive monoclonal antibodies
(
- Contribution to journal › Article
-
Mark
A novel process design for automated quality analysis in an integrated biopharmaceutical platform
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
In-silico Formulation of Iterative Learning Control for Chromatographic Purification of Biopharmaceuticals
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Automation of Modeling and Calibration of Integrated Preparative Protein Chromatography Systems
(
- Contribution to journal › Article
-
Mark
Toward Autonomous Production of mRNA-Therapeutics in the Light of Advanced Process Control and Traditional Control Strategies for Chromatography
(
- Contribution to journal › Article
- 2021
-
Mark
Optimal loading flow rate trajectory in monoclonal antibody capture chromatography
(
- Contribution to journal › Article
-
Mark
An integrated continuous downstream process with real-time control: A case study with periodic countercurrent chromatography and continuous virus inactivation
2021)(
- Working paper/Preprint › Preprint in preprint archive
-
Mark
An integrated continuous downstream process with real-time control : A case study with periodic countercurrent chromatography and continuous virus inactivation
(
- Contribution to journal › Article
- 2020
-
Mark
Trajectory optimization of an oscillating industrial two-stage evaporator utilizing a Python-Aspen Plus Dynamics toolchain
(
- Contribution to journal › Article
-
Mark
Continuous adsorption in food industry: The recovery of sinapic acid from rapeseed meal extract
(
- Contribution to journal › Article
-
Mark
Model-based design and control of a small-scale integrated continuous end-to-end mAb platform
(
- Contribution to journal › Article
-
Mark
Optimization study on periodic counter-current chromatography integrated in a monoclonal antibody downstream process
(
- Contribution to journal › Article
- 2019
-
Mark
Model-based monitoring of industrial reversed phase chromatography to predict insulin variants
(
- Contribution to journal › Article
-
Mark
Optimization of integrated chromatography sequences for purification of biopharmaceuticals
(
- Contribution to journal › Article
-
Mark
Single-shooting optimization of an industrial process through co-simulation of a modularized Aspen Plus Dynamics model
2019) 29th European Symposium on Computer Aided Process Engineering In Computer Aided Chemical Engineering 46. p.721-726(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Integration of a complete downstream process for the automated lab-scale production of a recombinant protein
(
- Contribution to journal › Article
- 2018
-
Mark
Multi-flowrate Optimization of the Loading Phase of a Preparative Chromatographic Separation
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Analysis of an Oscillating Two-Stage Evaporator System through Modelling and Simulation: an Industrial Case Study
(
- Contribution to journal › Article
-
Mark
Design of two-column batch-to-batch recirculation to enhance performance in ion-exchange chromatography
(
- Contribution to journal › Article
-
Mark
Designing an Autonomous Integrated Downstream Sequence From a Batch Separation Process − An Industrial Case Study
2018) In Biotechnology Journal(
- Contribution to journal › Article
-
Mark
Multicomponent inverse modeling of supercritical fluid extraction of carotenoids, chlorophyll A, ergosterol and lipids from microalgae
(
- Contribution to journal › Article
-
Mark
Mechanistic Modeling of Reversed-Phase Chromatography of Insulins within the Temperature Range 10–40 °C
(
- Contribution to journal › Article
-
Mark
Pareto-optimal reversed-phase chromatography separation of three insulin variants with a solubility constraint
(
- Contribution to journal › Article
- 2017
-
Mark
Design and control of integrated chromatography column sequences
(
- Contribution to journal › Article
-
Mark
Mechanistic Modeling of Reversed-Phase Chromatography of Insulins with Potassium Chloride and Ethanol as Mobile-Phase Modulators
(
- Contribution to journal › Article
-
Mark
Discretized multi-level elution trajectory: A proof-of-concept demonstration
(
- Contribution to journal › Article
-
Mark
Unbiased Selection of Decision Variables for Optimization
2017) 27th European Symposium on Computer Aided Process Engineering In Computer Aided Chemical Engineering 40. p.253-258(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Development and Optimization of a Single Column Analog Model for a Multi-Column Counter-Current Solvent Gradient Purification Process
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Robust Multi-Objective Optimization of Chromatographic Rare Earth Element Separation
(
- Contribution to journal › Article
- 2016
-
Mark
LCCC Workshop on Process Control
(2016) In Technical Reports TFRT-7649
- Book/Report › Conference proceeding (editor)
-
Mark
Method development in inverse modeling applied to supercritical fluid extraction of lipids
(
- Contribution to journal › Article
- 2015
-
Mark
Modeling Preparative Chromatographic Separation of Heavy Rare Earth Elements and Optimization of Thulium Purification
(
- Contribution to journal › Article
-
Mark
Combined effects of potassium chloride and ethanol as mobile phase modulators on hydrophobic interaction and reversed-phase chromatography of three insulin variants
(
- Contribution to journal › Article
-
Mark
Model-Based Comparison of Antibody Dimerization in Continuous and Batch-Wise Downstream Processing
(
- Contribution to journal › Article
-
Mark
Dynamic Multi-Objective Optimization of Batch Chromatographic Separation Processes
2015) 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering 37. p.815-820(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Prediction of reversible IgG1 aggregation occurring in a size exclusion chromatography column is enabled through a model based approach
(
- Contribution to journal › Article
-
Mark
Multi-Objective Optimization of Chromatographic Rare Earth Element Separation
(
- Contribution to journal › Article
-
Mark
Parameter Selection in the Parameter Estimation of Grade Transitions in a Polyethylene Plant
(
- Contribution to journal › Article
- 2014
-
Mark
Model-Based Comparison of Batch and Continuous Preparative Chromatography in the Separation of Rare Earth Elements
(
- Contribution to journal › Article
-
Mark
Prediction of IgG1 aggregation in solution.
(
- Contribution to journal › Article
-
Mark
Model-based design and integration of a two-step biopharmaceutical production process.
(
- Contribution to journal › Article
-
Mark
Modeling and robust pooling design of a preparative cation-exchange chromatography step for purification of monoclonal antibody monomer from aggregates.
(
- Contribution to journal › Article
-
Mark
Experimental productivity rate optimization of rare earth element separation through preparative solid phase extraction chromatography.
(
- Contribution to journal › Article
- 2013
-
Mark
Effects of uncertainties in experimental conditions on the estimation of adsorption model parameters in preparative chromatography
(
- Contribution to journal › Article
-
Mark
Model-based risk analysis of coupled process steps.
(
- Contribution to journal › Article
-
Mark
Mechanistic modelling of drug release from a polymer matrix using magnetic resonance microimaging.
(
- Contribution to journal › Article
-
Mark
Modeling the Synergies of Saline and Organic Modifiers on RPC Separation
2013) 2013 AIChE Annual Meeting(
- Contribution to conference › Abstract
- 2012
-
Mark
Modelling and optimisation of preparative chromatographic purification of europium.
(
- Contribution to journal › Article
-
Mark
Supporting Design and Control of a Reversed-Phase Chromatography Step by Mechanistic Modeling
(
- Contribution to journal › Article
-
Mark
Model-Based Process Challenge of an Industrial Ion-Exchange Chromatography Step
(
- Contribution to journal › Article
- 2011
-
Mark
Calibration of a polyethylene plant for grade change optimisations
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Optimization of preparative chromatographic separation of multiple rare earth elements.
(
- Contribution to journal › Article
- 2010
-
Mark
Pooling control in variable preparative chromatography processes.
(
- Contribution to journal › Article
-
Mark
Osmotic pumping release from ethyl-hydroxypropyl-cellulose-coated pellets: A new mechanistic model.
(
- Contribution to journal › Article
-
Mark
A mechanistic modelling approach to polymer dissolution using magnetic resonance microimaging.
(
- Contribution to journal › Article
- 2009
-
Mark
Determining Critical Process Parameters and Process Robustness in Preparative Chromatography - A Model-Based Approach
(
- Contribution to journal › Article
-
Mark
A Model-Based Approach to Determine the Design Space of Preparative Chromatography
(
- Contribution to journal › Article
-
Mark
Simultaneous modeling and optimization of preparative chromatography
(
- Contribution to journal › Published meeting abstract
-
Mark
Drug dissolution rate measurements - evaluation of the rotating disc method.
(
- Contribution to journal › Article
- 2008
-
Mark
Designing robust preparative purification processes with high performance
(
- Contribution to journal › Article
-
Mark
Heat and mass transport in a nonlinear fixed-bed catalytic reactor: Hot spots and thermal runaway
(
- Contribution to journal › Article
- 2007
-
Mark
Model based robustness analysis of an ion-exchange chromatography step
(
- Contribution to journal › Article
-
Mark
Modeling and optimization of preparative reversed-phase liquid chromatography for insulin purification
(
- Contribution to journal › Article
- 2006
-
Mark
Aspects of estimating parameter dependencies in a detailed chromatography model based on frontal experiments
(
- Contribution to journal › Article
-
Mark
Determination of diffusion coefficients of proteins in stationary phases by frontal chromatography
(
- Contribution to journal › Article
-
Mark
Constrained optimization of a preparative ion-exchange step for antibody purification
(
- Contribution to journal › Article
- 2005
-
Mark
Optimisation and robustness analysis of a hydrophobic interaction chromatography step
(
- Contribution to journal › Article
-
Mark
Computer guided optimization of adsorptive bioseparation processes
(
- Contribution to journal › Article
-
Mark
Aspects of Modeling a preparative ion-exchange step for antibody purification
(
- Contribution to journal › Article
-
Mark
Using computer simulation to assist in the robustness analysis of an ion-exchange chromatography step
(
- Contribution to journal › Article
-
Mark
Optimisation and robustness analysis of a hydrophobic interaction chromatography step
(
- Contribution to journal › Article
-
Mark
Optimization method for an ion exchange separation step
(
- Contribution to journal › Article
- 2004
-
Mark
Coupled diffusion and adsorption effects for multiple proteins in agarose gel
(
- Contribution to journal › Article
-
Mark
Effect of hindered diffusion on the adsorption of proteins in agarose gel using a pore model
(
- Contribution to journal › Article
-
Mark
Determination of protein diffusion coefficients in agarose gel with a diffusion cell
(
- Contribution to journal › Article
-
Mark
A methodology for estimation of mass transfer parameters in a detailed chromatography model based on frontal experiments
(
- Contribution to journal › Article
-
Mark
Model-based optimization of a preparative ion-exchange step for antibody purification
(
- Contribution to journal › Article
-
Mark
Methodologies for model calibration to assist the design of a preparative ion-exchange step for antibody purification
(
- Contribution to journal › Article
-
Mark
Simulation of the release from a multiparticulate system validated by single pellet and dose release experiments
(
- Contribution to journal › Article
-
Mark
Characterization of a continuous supermacroporous monolithic matrix for chromatographic separation of large bioparticles
(
- Contribution to journal › Article
- 2002
-
Mark
Mass transfer effects on the reaction rate for heterogeneously distributed immobilized yeast cells
(
- Contribution to journal › Article
-
Mark
Simulation and parametric study of a film-coated controlled-release pharmaceutical.
(
- Contribution to journal › Article
-
Mark
Parameter estimation of protein chromatographic processes based on breakthrough curves
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 1998
-
Mark
Object-Oriented Modelling of Thermal Power Plants
(
- Contribution to journal › Article
- 1997
-
Mark
Processreglering - föreläsningsanteckningar 1997
1997) In Technical Reports TFRT-7560(
- Book/Report › Report
- 1996
-
Mark
Simulation of Process Systems - A PhD Course
1996) In Technical Reports TFRT-7550(
- Book/Report › Report
-
Mark
Simulation of a Thermal Power Plant Using an Object-Oriented Model Database
1996) 13th IFAC World Congress(
- Contribution to conference › Paper, not in proceeding
- 1995
-
Mark
Omola, OmSim och K2 - en kort kurs
1995) In Technical Reports TFRT-7535(
- Book/Report › Report
-
Mark
Process Modeling - A PhD Course
1995) In Technical Reports TFRT-7536(
- Book/Report › Report
-
Mark
An Object-Oriented Model Database for Thermal Power Plants
1995) Eurosim '95 Simulation Congress(
- Contribution to conference › Paper, not in proceeding
-
Mark
Experiences of Developing Process Model Libraries in Omola
1995) First International Conference on Intelligent Systems in Process Engineering, ISPE'95(
- Contribution to conference › Paper, not in proceeding
- 1994
-
Mark
K2 Model Database - Tutorial and Reference Manual
1994) In Technical Reports TFRT-7528(
- Book/Report › Report
-
Mark
Object-Oriented Modelling and Simulation of a Power Plant : Application Study in the K2 Project
1994) In Technical Reports TFRT-7527(
- Book/Report › Report
-
Mark
Modellering och simulering av satsvisa processer med OMOLA
1994) Reglermöte 1994(
- Contribution to conference › Paper, not in proceeding
-
Mark
Guidelines for Process Model Libraries using an Object-Oriented Approach
1994) European Simulation Multiconference, 1994(
- Contribution to conference › Paper, not in proceeding
-
Mark
Dynamic Modeling of Chemical Processes using Omola
1994) 4th European Symposium on Computer Aided Process Engineering(
- Contribution to conference › Paper, not in proceeding
-
Mark
Modeling and Simulation of a Batch Process in Omola
1994) 36th SIMS Simulation Conference, 1994(
- Contribution to conference › Paper, not in proceeding
-
Mark
Dynamic Modeling of Chemical Processes using OMOLA
(
- Contribution to journal › Article
- 1993
-
Mark
Object-Oriented Modeling of Chemical Processes
1993) In PhD Thesis TFRT-1041(
- Thesis › Doctoral thesis (monograph)
-
Mark
A Chemical Plant Model in Omola : The code
1993) In Technical Reports TFRT-7507(
- Book/Report › Report
-
Mark
Modeling Process Control System in Omola
1993) 12th IFAC World Congress(
- Contribution to conference › Paper, not in proceeding
- 1992
-
Mark
Object-Oriented Chemical Process Modelling in Omola
1992) 1992 IEEE Symposium on Computer-Aided Control System Design, CACSD'92(
- Contribution to conference › Paper, not in proceeding
- 1991
-
Mark
En on-linesimulator för operatörsstöd
1991) In Research Reports TFRT-3209(
- Book/Report › Report
-
Mark
On the Architecture of CACE Environments
1991) IFAC Symposium Computer Aided Design in Control Systems, CADCS'91(
- Contribution to conference › Paper, not in proceeding
- 1990
-
Mark
Modelling of Sugar Crystalization Process
1990) Preprints of the DUP Conference 1990(
- Contribution to conference › Paper, not in proceeding
-
Mark
A Kernel for Object-Oriented CACE
1990) Nordic CACE Symposimum(
- Contribution to conference › Paper, not in proceeding
-
Mark
An Integrated Environment for Design of Control Systems
1990) Reglermöte 1990(
- Contribution to conference › Paper, not in proceeding
-
Mark
Object-Oriented Modelling of a Controlled Chemical Process
1990) 11th IFAC World Congress(
- Contribution to conference › Paper, not in proceeding
-
Mark
Modelling and Simulation of Sugar Crystalization Process
1990) DUP conference 1990(
- Contribution to conference › Paper, not in proceeding
- 1989
-
Mark
Structured Modelling of Chemical Processes with Control Systems
1989) In Technical Reports TFRT-7439(
- Book/Report › Report
-
Mark
Structured Modelling of Chemical Processes : An Object-Oriented Approach
1989) In Research Reports TFRT-3203(
- Thesis › Licentiate thesis
-
Mark
Tools for Model Development and Simulation
1989) SAIS '89 Workshop(
- Contribution to conference › Paper, not in proceeding
-
Mark
Object-Oriented Modelling of a Controlled Chemical Process
1989) In Technical Reports TFRT-7428(
- Book/Report › Report
-
Mark
Structured Modelling of Chemical Processes with Control Systems
1989) Annual AIChE Meeting 1989(
- Contribution to conference › Paper, not in proceeding
- 1988
-
Mark
A Small System-Structuring System in Scheme
1988) In Technical Reports TFRT-7379(
- Book/Report › Report
- 1987
-
Mark
Experiences of Describing a Distillation Column in Some Modelling Languages
1987) In Technical Reports TFRT-7362(
- Book/Report › Report
- 1986
-
Mark
LQG-I/O - A CTRL-C Library for LQG Design
1986) In Technical Reports TFRT-7329(
- Book/Report › Report