Immunology
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- 2024
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Mark
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue
(
- Contribution to journal › Article
- 2022
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Mark
Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response
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- Contribution to journal › Article
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Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes
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- Contribution to journal › Article
- 2021
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Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation
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- Contribution to journal › Article
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Minor alterations in the intestinal microbiota composition upon Rotavirus infection do not affect susceptibility to DSS colitis
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- Contribution to journal › Article
- 2020
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Mark
Self-reactive T cells induce and perpetuate chronic relapsing arthritis
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- Contribution to journal › Article
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Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity
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- Contribution to journal › Article
- 2019
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Pharmacologic exhaustion of suppressor cells with tasquinimod enhances bacterial clearance during tuberculosis
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- Contribution to journal › Letter
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SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation
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- Contribution to journal › Article
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Wnt5a is a TLR2/4-ligand that induces tolerance in human myeloid cells
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- Contribution to journal › Article
- 2018
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Mark
Paquinimod prevents development of diabetes in the non-obese diabetic (NOD) mouse
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- Contribution to journal › Article
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Mark
S100A9 in inflammatory disease: a potential target for amelioration
(
- Thesis › Doctoral thesis (compilation)
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Mark
The immunomodulatory quinoline-3-carboxamide paquinimod reverses established fibrosis in a novel mouse model for liver fibrosis
(
- Contribution to journal › Article
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Immunity to gastrointestinal nematode infections
(
- Contribution to journal › Scientific review
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Induction of S100A9 homodimer formation in vivo
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- Contribution to journal › Article
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Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
(
- Contribution to journal › Article
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Mark
Streptococcal M protein promotes IL-10 production by cGAS-independent activation of the STING signaling pathway
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- Contribution to journal › Article
- 2017
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Mark
Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus
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- Contribution to journal › Article
- 2016
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Mark
Structural and biochemical characterization of two heme binding sites on α1-microglobulin using site directed mutagenesis and molecular simulation.
(
- Contribution to journal › Article
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Mark
IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition.
(
- Contribution to journal › Article
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Mark
Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.
2016) In Arthritis & Rheumatology(
- Contribution to journal › Article
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Mark
MLH1 Ile219Val polymorphism in argentinean families with suspected lynch syndrome
(
- Contribution to journal › Article
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Mark
CD14 is a co-receptor for TLR4 in the S100A9-induced pro-inflammatory response in monocytes
(
- Contribution to journal › Article
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Eosinophils may play regionally disparate roles in influencing IgA+ plasma cell numbers during large and small intestinal inflammation
(
- Contribution to journal › Article
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Mark
S100A9 in inflammation
2016)(
- Thesis › Doctoral thesis (compilation)
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Mark
A new mouse model that spontaneously develops chronic liver inflammation and fibrosis
(
- Contribution to journal › Article
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A reduced population of CD103+CD11b+ dendritic cells has a limited impact on oral Salmonella infection
(
- Contribution to journal › Article
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Paquinimod reduces skin fibrosis in tight skin 1 mice, an experimental model of systemic sclerosis
(
- Contribution to journal › Article
- 2015
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Mark
Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.
(
- Contribution to journal › Article
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Mark
Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells.
(
- Contribution to journal › Article
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A1M/α1-microglobulin is proteolytically activated by myeloperoxidase, binds its heme group and inhibits low density lipoprotein oxidation.
(
- Contribution to journal › Article
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Mark
A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit.
(
- Contribution to journal › Article
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Mark
Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models
(
- Contribution to journal › Article
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Mark
Effect of quinoline-3-carboxamides on myeloid cells in inflammation and cancer
(
- Thesis › Doctoral thesis (compilation)
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Mark
Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion.
(
- Contribution to journal › Article
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Mark
S100A9 as a pharmacological target molecule in inflammation and cancer.
(
- Contribution to journal › Article
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Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
(
- Contribution to journal › Article
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Mark
Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.
(
- Contribution to journal › Article
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Myeloid-related protein 14 promote inflammation and injury in meningitis.
(
- Contribution to journal › Article
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Mark
MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota.
(
- Contribution to journal › Article
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Mark
S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.
(
- Contribution to journal › Article
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Mark
A phase 1 dose-escalation study of antibody BI-505 in relapsed/refractory multiple myeloma.
(
- Contribution to journal › Article
- 2014
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Mark
Characterization of heme binding to recombinant α1-microglobulin.
(
- Contribution to journal › Article
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Mark
Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment.
(
- Contribution to journal › Article
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Mark
A1M/α1-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia.
(
- Contribution to journal › Article
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Mark
Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.
(
- Contribution to journal › Article
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Mark
The quinoline-3-carboxamide paquinimod (ABR-215757) reduces leukocyte recruitment during sterile inflammation: Leukocyte- and context-specific effects.
(
- Contribution to journal › Article
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Mark
High density of S100A9 positive inflammatory cells in prostate cancer stroma is associated with poor outcome.
(
- Contribution to journal › Article
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Somatic cells with a heavy mitochondrial DNA mutational load render iPS cells with distinct differentiation defects.
(
- Contribution to journal › Article
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Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency
(
- Contribution to journal › Article
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Mark
Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity.
(
- Contribution to journal › Article
- 2013
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Mark
Common Interactions between S100A4 and S100A9 Defined by a Novel Chemical Probe.
(
- Contribution to journal › Article
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Mark
Human S100A9 Protein Is Stabilized by Inflammatory Stimuli via the Formation of Proteolytically-Resistant Homodimers.
(
- Contribution to journal › Article
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Mark
Effect of the quinoline-3-carboxamide ABR-215757 during inflammation
(
- Thesis › Doctoral thesis (compilation)
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Mark
Global and 3D Spatial Assessment of Neuroinflammation in Rodent Models of Multiple Sclerosis.
(
- Contribution to journal › Article
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Mark
Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment
(
- Contribution to journal › Article
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Mark
Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors.
(
- Contribution to journal › Article
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PD-L1 Expression by Neurons Nearby Tumors Indicates Better Prognosis in Glioblastoma Patients.
(
- Contribution to journal › Article
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A human icam-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
(
- Contribution to journal › Article
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Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.
(
- Contribution to journal › Article
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In silico peptide-binding predictions of passerine MHC class I reveal similarities across distantly related species, suggesting convergence on the level of protein function.
(
- Contribution to journal › Article
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Mark
Tapasin Facilitation of Natural HLA-A and -B Allomorphs Is Strongly Influenced by Peptide Length, Depends on Stability, and Separates Closely Related Allomorphs.
(
- Contribution to journal › Article
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Mark
The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function.
(
- Contribution to journal › Article
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Mark
Amelioration of Experimental Autoimmune Encephalomyelitis by the Quinoline-3-Carboxamide Paquinimod (ABR-215757): Reduced Priming of Proinflammatory Effector CD4(+) T Cells.
(
- Contribution to journal › Article
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Mark
An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.
(
- Contribution to journal › Article
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Mark
Cocaine- and amphetamine-regulated transcript is expressed in adipocytes and regulate lipid- and glucose homeostasis.
(
- Contribution to journal › Article
- 2012
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Mark
Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections
(
- Contribution to journal › Article
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Mark
CD11b(+)Ly6C(++)Ly6G(-) cells show distinct function in mice with chronic inflammation or tumor burden
(
- Contribution to journal › Article
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Mark
S100A9 Interaction with TLR4 Promotes Tumor Growth.
(
- Contribution to journal › Article
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Mark
Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species
(
- Contribution to journal › Article
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Mark
Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate
(
- Contribution to journal › Article
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Mark
Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice
(
- Contribution to journal › Article
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Mark
Cartilage oligomeric matrix protein specific antibodies are pathogenic
(
- Contribution to journal › Article
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Mark
Induction of NFκB responses by the S100A9 protein is TLR4-dependent.
(
- Contribution to journal › Article
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Mark
S100A9 and tumor growth.
(
- Contribution to journal › Article
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Mark
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050)
(
- Contribution to journal › Article
- 2011
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Mark
Molecular Mechanisms in Hematopoietic Stem Cell Aging
(
- Thesis › Doctoral thesis (compilation)
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Mark
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia
(
- Contribution to journal › Article
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Mark
Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice
(
- Contribution to journal › Article
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Mark
THE ROLE OF DENDRITIC CELLS AND TYPE I INTERFERON IN THE GENERATION AND FUNCTION OF T FOLLICULAR HELPER CELLS
(
- Thesis › Doctoral thesis (compilation)
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Mark
S100A8/A9 in bleomycin-induced skin fibrosis
2011) 31st European Workshop for Rheumatology Research In Annals of the Rheumatic Diseases 70(Suppl. 2).(
- Contribution to journal › Published meeting abstract
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Mark
Threonine 153 in P47(PHOX) Regulates ROS Production by the NADPH Oxidase NOX2
2011) 40th Scandinavian-Society for Immunology Meeting In Scandinavian Journal of Immunology 73(4). p.71-71(
- Contribution to journal › Published meeting abstract
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Mark
Phenotype and function of intestinal CD103+ dendritic cells
(
- Thesis › Doctoral thesis (compilation)
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Mark
A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis
(
- Contribution to journal › Article
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Mark
Collagen Type II and a Thermo-Responsive Polymer of N-Isopropylacrylamide Induce Arthritis Independent of Toll-Like Receptors A Strong Influence by Major Histocompatibility Complex Class II and Ncf1 Genes
(
- Contribution to journal › Article
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Mark
Positioning of a Polymorphic Quantitative Trait Nucleotide in the Ncf1 Gene Controlling Oxidative Burst Response and Arthritis Severity in Rats.
(
- Contribution to journal › Article
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Mark
The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor
(
- Contribution to journal › Article
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Mark
High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice
(
- Contribution to journal › Article
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Mark
Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus
(
- Contribution to journal › Article
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Mark
Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary osteoporosis.
(
- Contribution to journal › Article
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Mark
Tapasin discriminates peptide-human leukocyte antigen-A*02:01 complexes fromed with natural ligands
(
- Contribution to journal › Article
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Mark
Dietary quinic acid supplied as the nutritional supplement AIO + AC-11® leads to induction of micromolar levels of nicotinamide and tryptophan in the urine.
(
- Contribution to journal › Article
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Mark
IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors
(
- Contribution to journal › Article
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Mark
An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes.
(
- Contribution to journal › Article
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Mark
Specific effect of immunomodulatory quinoline-3-carboxamide ABR-215757 in GM-CSF stimulated bone marrow cell cultures: Block of initiation of proliferation of Gr-1(+) cells.
(
- Contribution to journal › Article
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Mark
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.
(
- Contribution to journal › Article
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Mark
CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species.
(
- Contribution to journal › Article
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Mark
Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects.
(
- Contribution to journal › Article
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Mark
Flow cytometry-based identification of immature myeloerythroid development.
(
- Contribution to journal › Article
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Mark
Pathogenic Autoreactive B Cells Are Not Negatively Selected toward Matrix Protein Collagen II.
(
- Contribution to journal › Article