Roger Olsson
- Chemical Biology and Therapeutics
- MultiPark: Multidisciplinary research focused on Parkinson´s disease
- Centre for Analysis and Synthesis
- NanoLund: Centre for Nanoscience
- Centre for Analysis and Synthesis
- LTH Profile Area: Nanoscience and Semiconductor Technology
- LU Profile Area: Light and Materials
- LUCC: Lund University Cancer Centre
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- 2024
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Mark
High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer
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- Contribution to journal › Article
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Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity
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- Contribution to journal › Article
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In situ assembly of an injectable cardiac stimulator
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- Contribution to journal › Article
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Tuning the Emission of Bis-ethylenedioxythiophene-thiophenes upon Aggregation
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- Contribution to journal › Article
- 2023
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In situ assembly of bioresorbable organic bioelectronics in the brain
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- Contribution to journal › Article
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Metabolite-induced in vivo fabrication of substrate-free organic bioelectronics
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Ciclopirox Ethanolamine Preserves the Immature State of Human HSCs by Mediating Intracellular Iron Content
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- Contribution to journal › Article
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Enzymatically Polymerized Organic Conductors on Model Lipid Membranes
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- Contribution to journal › Article
- 2022
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Method Matters : Exploring Alkoxysulfonate-Functionalized Poly(3,4-ethylenedioxythiophene) and Its Unintentional Self-Aggregating Copolymer toward Injectable Bioelectronics
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- Contribution to journal › Article
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Mark
High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model
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- Contribution to journal › Article
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Glioblastoma CD105+ cells define a SOX2- cancer stem cell-like subpopulation in the pre-invasive niche
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- Contribution to journal › Article
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Rational Materials Design for In Operando Electropolymerization of Evolvable Organic Electrochemical Transistors
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- Contribution to journal › Article
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Organic electrochemical neurons and synapses with ion mediated spiking
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- Contribution to journal › Article
- 2021
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A Biomimetic Evolvable Organic Electrochemical Transistor
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- Contribution to journal › Article
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Seamless integration of bioelectronic interface in an animal model via in vivo polymerization of conjugated oligomers
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FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation
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- Contribution to journal › Article
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Identification of potential chemical compounds enhancing generation of enucleated cells from immortalized human erythroid cell lines
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- Contribution to journal › Article
- 2020
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Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition
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- Contribution to journal › Article
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Enantiomeric N-substituted phthalimides with excitatory amino acids protect zebrafish larvae against PTZ-induced seizures
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- Contribution to journal › Article
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Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model
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- Contribution to journal › Article
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Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
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- Contribution to journal › Article
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Discovery of Procognitive Antipsychotics by Combining Muscarinic M1 Receptor Structure-Activity Relationship with Systems Response Profiles in Zebrafish Larvae
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- Contribution to journal › Article
- 2019
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A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia
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- Contribution to journal › Article
- 2018
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Osmotic Concentration of Zebrafish (Danio rerio) Body Fluids is Lower in Larvae than in Adults
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- Contribution to journal › Article
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Evaluation of Drug Exposure and Metabolism in Locust and Zebrafish Brains Using Mass Spectrometry Imaging
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- Contribution to journal › Article
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Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity
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- Contribution to journal › Article
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Small Molecule Screens Identify CDK8-Inhibitors As Candidate Diamond-Blackfan Anemia Drugs
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- Contribution to journal › Published meeting abstract
- 2017
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Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
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- Contribution to journal › Article
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Action sequencing in the spontaneous swimming behavior of zebrafish larvae - implications for drug development
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- Contribution to journal › Article
- 2016
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Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation.
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- Contribution to journal › Article
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Small molecule screen identifies differentiation-promoting compounds targeting genetically diverse acute myeloid leukaemia.
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- Contribution to journal › Article
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An ex Vivo Model for Evaluating Blood-Brain Barrier Permeability, Efflux, and Drug Metabolism.
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- Contribution to journal › Article
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Behavioral Analysis of Dopaminergic Activation in Zebrafish and Rats Reveals Similar Phenotypes
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- Contribution to journal › Article
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Estrogen Receptor Beta Selective Agonists as Agents to Treat Chemotherapeutic-Induced Neuropathic Pain
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- Contribution to journal › Article
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Regio- and Stereoselective Alkylation of Pyridine-N-oxides : Synthesis of Substituted Piperidines and Pyridines
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- Contribution to journal › Article
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Small molecules increase direct neural conversion of human fibroblasts
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- Contribution to journal › Article
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Identification of V-ATPase as a molecular sensor of SOX11-levels and potential therapeutic target for mantle cell lymphoma
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- Contribution to journal › Article
- 2015
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Mark
Using visual lateralization to model learning and memory in zebrafish larvae.
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- Contribution to journal › Article
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Synthesis and Biological Evaluation of Second-Generation Tropanol-Based Androgen Receptor Modulators
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- Contribution to journal › Article
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Therapeutic Targeting of Nuclear Gamma-Tubulin in RB1-negative Tumors.
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- Contribution to journal › Article
- 2014
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Mark
Apicidin Sensitizes Pancreatic Cancer Cells to Gemcitabine by Epigenetically Regulating MUC4 Expression.
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- Contribution to journal › Article
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Bexarotene prodrugs: Targeting through cleavage by NQO1 (DT-diaphorase).
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- Contribution to journal › Article
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Impact of estrogen receptor beta activation on functional recovery after experimental stroke.
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- Contribution to journal › Article
- 2013
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Mark
Nonsteroidal Selective Androgen Receptor Modulators and Selective Estrogen Receptor β Agonists Moderate Cognitive Deficits and Amyloid-β Levels in a Mouse Model of Alzheimer's Disease.
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- Contribution to journal › Article
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Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson's Disease
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- Contribution to journal › Article
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Mark
AC-186, a Selective Nonsteroidal Estrogen Receptor beta Agonist, Shows Gender Specific Neuroprotection in a Parkinson's Disease Rat Model
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- Contribution to journal › Article
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Design of a Highly Selective and Potent Class of Non-planar Estrogen Receptor Agonists
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- Contribution to journal › Article
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The A-CD analogue of 16 beta,17 alpha-estriol is a potent and highly selective estrogen receptor beta agonist
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- Contribution to journal › Article
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A Robust Screening Assay For Diamond Blackfan Anemia Candidate Drugs
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- Contribution to journal › Published meeting abstract
- 2012
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Mark
Enantioselective Synthesis of Substituted Piperidines by Addition of Aryl Grignard Reagents to Pyridine N-Oxides.
2012) In Organic Letters(
- Contribution to journal › Article
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Mark
Discovery of potential antipsychotic agents possessing pro-cognitive properties
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- Contribution to journal › Article
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Mark
Selective mode of action of guanidine-containing non-peptides at human NPFF receptors
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- Contribution to journal › Article
- 2011
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Mark
Can alpha-synuclein be targeted in novel therapies for Parkinson's disease?
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- Contribution to journal › Article
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Characterization of highly efficacious allosteric agonists of the human calcium-sensing receptor
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- Contribution to journal › Article
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Reactions between Grignard reagents and heterocyclic N-oxides : Stereoselective synthesis of substituted pyridines, piperidines, and piperazines
(
- Contribution to journal › Scientific review
- 2010
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Discovery of a class of calcium sensing receptor positive allosteric modulators; 1-(benzothiazol-2-yl)-1-phenylethanols
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- Contribution to journal › Article
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Mark
Synthesis of substituted 4-pyridones and 4-aminopyridinium salts via a one-pot pyridine synthesis
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- Contribution to journal › Article
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Efficient, mild and completely regioselective synthesis of substituted pyridines
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- Contribution to journal › Article
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Complete regioselective addition of grignard reagents to pyrazine N-oxides, toward an efficient enantioselective synthesis of substituted piperazines
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- Contribution to journal › Article
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Asymmetric synthesis of a tricyclic benzofuran motif : A privileged core structure in biologically active molecules
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- Contribution to journal › Article
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Optimization of isochromanone based urotensin II receptor agonists
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- Contribution to journal › Article
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Neuropeptide FF receptors have opposing modulatory effects on nociception
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- Contribution to journal › Article
- 2009
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Mark
Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists
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- Contribution to journal › Article
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Mark
Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators
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- Contribution to journal › Article
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Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor β ligands
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- Contribution to journal › Article
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Discovery of non-peptidergic MrgX1 and MrgX2 receptor agonists and exploration of an initial SAR using solid-phase synthesis
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- Contribution to journal › Article
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The regio- and stereoselective synthesis of trans-2,3-dihydropyridine n-oxides and piperidines
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- Contribution to journal › Article
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Synthesis and evaluation of dibenzothiazepines : A novel class of selective cannabinoid-1 receptor inverse agonists
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- Contribution to journal › Article
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Novel and potent small-molecule urotensin II receptor agonists
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- Contribution to journal › Article
- 2008
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Discovery of potent and selective small-molecule PAR-2 agonists
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- Contribution to journal › Article
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Identification and characterization of novel small-molecule protease-activated receptor 2 agonists
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- Contribution to journal › Article
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Identification of novel selective V2 receptor non-peptide agonists
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- Contribution to journal › Article
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Selective synthesis of 2-substituted pyridine N-oxides via directed ortho-metallation using Grignard reagents
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- Contribution to journal › Article
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Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist
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- Contribution to journal › Article
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Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist
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- Contribution to journal › Article
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Identification of the first synthetic steroidogenic factor 1 inverse agonists : Pharmacological modulation of steroidogenic enzymes
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- Contribution to journal › Article
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Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator
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- Contribution to journal › Article
- 2007
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Reaction of pyridine N-oxides with Grignard reagents : a stereodefined synthesis of substituted dienal oximes
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- Contribution to journal › Article
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Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists
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- Contribution to journal › Article
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Design, parallel synthesis and SAR of novel urotensin II receptor agonists
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- Contribution to journal › Article
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Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer
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- Contribution to journal › Article
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Synthesis of 2-substituted pyridines via a regiospecific alkylation, alkynylation, and arylation of pyridine N-oxides
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- Contribution to journal › Article
- 2006
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Iron-catalyzed cross-coupling of imidoyl chlorides with Grignard reagents
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- Contribution to journal › Article
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Novel potent and efficacious nonpeptidic urotensin II receptor agonists
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- Contribution to journal › Article
- 2005
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Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist
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- Contribution to journal › Article
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Identification of novel subtype selective RAR agonists
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- Contribution to journal › Article
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Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors : Identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist
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- Contribution to journal › Article
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Isochromanone-based urotensin-II receptor agonists
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- Contribution to journal › Article
- 2004
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The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
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- Contribution to journal › Article
- 2003
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A combinatorial scaffold approach based upon a multicomponent reaction
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- Contribution to journal › Article
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Efficient Solution-Phase Parallel Synthesis of 4-Substituted N-Protected Piperidines
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- Contribution to journal › Article
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Solution-phase parallel Wittig olefination : Synthesis of substituted 1,2-diarylethanes
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- Contribution to journal › Article
- 2002
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A Novel Metal Iodide Promoted Three-Component Synthesis of Substituted Pyrrolidines
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- Contribution to journal › Article
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One-pot three-component reaction for the synthesis of α-(aminoethyl)-α,β-enones
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- Contribution to journal › Article
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Discovery of the first nonpeptide agonist of the GPR14/Urotensin-II receptor : 3-(4-Chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954)
(
- Contribution to journal › Article
- 2001
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Mark
General combinatorial synthesis of tertiary amines on solid support. A novel conditional release strategy based on traceless linking at nitrogen
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- Contribution to journal › Article
- 2000
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Mark
Temporary in situ aluminum and zinc tethering in Diels-Alder reactions
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- Contribution to journal › Article
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Multistep solution-phase parallel synthesis of spiperone analogues
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- Contribution to journal › Article
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Microwave-assisted solvent-free parallel synthesis of thioamides
(
- Contribution to journal › Article
- 1998
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Mark
Alkylative cleavage of the endo-cyclic C-O bond in lactol ethers employing organometallic reagents
(
- Contribution to journal › Article