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- 2019
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Mark
Pharmacologic exhaustion of suppressor cells with tasquinimod enhances bacterial clearance during tuberculosis
(
- Contribution to journal › Letter
- 2018
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Mark
Induction of S100A9 homodimer formation in vivo
(
- Contribution to journal › Article
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Mark
Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
(
- Contribution to journal › Article
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Mark
Paquinimod prevents development of diabetes in the non-obese diabetic (NOD) mouse
(
- Contribution to journal › Article
- 2017
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Mark
Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus
(
- Contribution to journal › Article
- 2016
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Mark
IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition.
(
- Contribution to journal › Article
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Mark
CD14 is a co-receptor for TLR4 in the S100A9-induced pro-inflammatory response in monocytes
(
- Contribution to journal › Article
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Mark
The anti-tumor effect of the quinoline-3-carboxamide tasquinimod : Blockade of recruitment of CD11b+ Ly6Chi cells to tumor tissue reduces tumor growth
(
- Contribution to journal › Article
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Mark
Paquinimod reduces skin fibrosis in tight skin 1 mice, an experimental model of systemic sclerosis
(
- Contribution to journal › Article
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Mark
Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.
2016) In Arthritis & Rheumatology(
- Contribution to journal › Article
- 2015
-
Mark
Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells.
(
- Contribution to journal › Article
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Mark
Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.
(
- Contribution to journal › Article
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Mark
Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models
(
- Contribution to journal › Article
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Mark
S100A9 as a pharmacological target molecule in inflammation and cancer.
(
- Contribution to journal › Article
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Mark
Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion.
(
- Contribution to journal › Article
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Mark
Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
(
- Contribution to journal › Article
-
Mark
Myeloid-related protein 14 promote inflammation and injury in meningitis.
(
- Contribution to journal › Article
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Mark
S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.
(
- Contribution to journal › Article
- 2014
-
Mark
Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment.
(
- Contribution to journal › Article
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Mark
The quinoline-3-carboxamide paquinimod (ABR-215757) reduces leukocyte recruitment during sterile inflammation: Leukocyte- and context-specific effects.
(
- Contribution to journal › Article
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Mark
High density of S100A9 positive inflammatory cells in prostate cancer stroma is associated with poor outcome.
(
- Contribution to journal › Article
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Mark
Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity.
(
- Contribution to journal › Article
- 2013
-
Mark
Common Interactions between S100A4 and S100A9 Defined by a Novel Chemical Probe.
(
- Contribution to journal › Article
-
Mark
Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors.
(
- Contribution to journal › Article
-
Mark
Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment
(
- Contribution to journal › Article
-
Mark
Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.
(
- Contribution to journal › Article
-
Mark
The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function.
(
- Contribution to journal › Article
-
Mark
Amelioration of Experimental Autoimmune Encephalomyelitis by the Quinoline-3-Carboxamide Paquinimod (ABR-215757): Reduced Priming of Proinflammatory Effector CD4(+) T Cells.
(
- Contribution to journal › Article
- 2012
-
Mark
CD11b(+)Ly6C(++)Ly6G(-) cells show distinct function in mice with chronic inflammation or tumor burden
(
- Contribution to journal › Article
-
Mark
Induction of NFκB responses by the S100A9 protein is TLR4-dependent.
(
- Contribution to journal › Article
-
Mark
S100A9 Interaction with TLR4 Promotes Tumor Growth.
(
- Contribution to journal › Article
-
Mark
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050)
(
- Contribution to journal › Article
-
Mark
S100A9 and tumor growth.
(
- Contribution to journal › Article
- 2011
-
Mark
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia
(
- Contribution to journal › Article
-
Mark
Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus
(
- Contribution to journal › Article
-
Mark
Specific effect of immunomodulatory quinoline-3-carboxamide ABR-215757 in GM-CSF stimulated bone marrow cell cultures: Block of initiation of proliferation of Gr-1(+) cells.
(
- Contribution to journal › Article
- 2010
-
Mark
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
(
- Contribution to journal › Article
-
Mark
Indoleamine 2,3-dioxygenase (IDO) activity influence tumor growth in the TRAMP prostate cancer model.
(
- Contribution to journal › Article
-
Mark
Selective depletion of splenic CD4 dendritic cells in mice treated with immunomodulatory quinoline-3-carboxamide ABR-215757.
(
- Contribution to journal › Article
- 2009
-
Mark
From the fetal liver to spleen and gut: the highway to natural antibody
(
- Contribution to journal › Article
-
Mark
Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.
(
- Contribution to journal › Article
-
Mark
Antioxidant metabolism induced by quinic acid. increased urinary excretion of tryptophan and nicotinamide.
(
- Contribution to journal › Article
- 2008
-
Mark
Effect on interferon-inducible gene expression signature by ABR215757, a new drug in development for SLE
2008) 72nd Annual Scientific Meeting of the American-College-of-Rheumatology/43rd Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals In Arthritis and Rheumatism 58(9). p.567-568(
- Contribution to journal › Published meeting abstract
-
Mark
A subset of dendritic cells express joining chain (J-chain) protein
(
- Contribution to journal › Article
-
Mark
IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis
(
- Contribution to journal › Article
- 2007
-
Mark
Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria
(
- Contribution to journal › Article
- 2006
-
Mark
CArG box-binding factor-A interacts with multiple motifs in immunoglobulin promoters and has a regulated subcellular distribution.
(
- Contribution to journal › Article
-
Mark
Joining-chain (J-chain) negative mice are B cell memory deficient.
(
- Contribution to journal › Article
-
Mark
Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer.
(
- Contribution to journal › Article
-
Mark
The kappa promoter penta-decamer binding protein CBF-A interacts specifically with nucleophosmin in the nucleus only.
(
- Contribution to journal › Article
-
Mark
SPI-C and STAT6 can cooperate to stimulate IgE germline transcription.
(
- Contribution to journal › Article
- 2005
-
Mark
Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100(R).
(
- Contribution to journal › Article
- 2004
-
Mark
Identification of a novel thioredoxin-related protein, PC-TRP, which is preferentially expressed in plasma cells.
(
- Contribution to journal › Article
-
Mark
Frequent activation of CArG binding factor-A expression and binding in N-methyl-N-nitrosourea-induced rat mammary carcinomas
(
- Contribution to journal › Article
- 2003
-
Mark
An extract of Uncaria tomentosa inhibiting cell division and NF-kappaB activity without inducing cell death.
(
- Contribution to journal › Article
-
Mark
IFN-beta Gene Deletion Leads to Augmented and Chronic Demyelinating Experimental Autoimmune Encephalomyelitis.
(
- Contribution to journal › Article
-
Mark
SPI-C, a PU-box binding ETS protein expressed temporarily during B-cell development and in macrophages, contains an acidic transactivation domain located to the N-terminus.
(
- Contribution to journal › Article
-
Mark
Was it there all the time?
(
- Contribution to journal › Scientific review
-
Mark
Strong Differential Regulation of Serum and Mucosal IgA Responses as Revealed in CD28-Deficient Mice Using Cholera Toxin Adjuvant.
(
- Contribution to journal › Article
-
Mark
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
(
- Contribution to journal › Article
-
Mark
Differential usage of IκBα and IκBβ in regulation of apoptosis versus gene expression
(
- Contribution to journal › Article
- 2002
-
Mark
Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells.
(
- Contribution to journal › Article
-
Mark
Ly6C expression differentiates plasma cells from other B cell subsets in mice.
(
- Contribution to journal › Article
-
Mark
Mechanism of action for N-substituted benzamide-induced apoptosis.
(
- Contribution to journal › Article
-
Mark
Genomic structure of mouse SPI-C and genomic structure and expression pattern of human SPI-C.
(
- Contribution to journal › Article
- 2001
-
Mark
Transcription factor AP-4 is a ligand for immunoglobulin-κ promoter E-box elements
(
- Contribution to journal › Article
-
Mark
T-cell receptor repertoire in human germinal centres
(
- Contribution to journal › Article
- 2000
-
Mark
Purification and cloning of type A/B hnRNP protein involved in transcriptional activation from the rat spi 2 gene GAGA box
(
- Contribution to journal › Article
- 1999
-
Mark
Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development
(
- Contribution to journal › Article
-
Mark
Promotion of immunoglobulin gene transcription
(
- Contribution to journal › Article
- 1998
-
Mark
Purification and characterization of a protein binding to the SP6 κ promoter : A potential role for CArG-box binding factor-A in κ transcription
(
- Contribution to journal › Article
-
Mark
Conserved sequence elements in K promoters from mice and humans : Implications for transcriptional regulation and repertoire expression
(
- Contribution to journal › Article
-
Mark
Differentiation-specific, octamer-dependent costimulation of κ transcription
(
- Contribution to journal › Article
- 1997
-
Mark
Diverse transcription factors are involved in the quantitative regulation of transcriptional activation of κ promoters
(
- Contribution to journal › Article
- 1996
-
Mark
Somatic mutation of immunoglobulin V genes in vitro
(
- Contribution to journal › Article
- 1995
-
Mark
The effect of carrier and carrier priming on the kinetics and pattern of somatic mutation in the V chi Ox1 gene
(
- Contribution to journal › Article
-
Mark
Cell-cycle kinetics of proliferating mouse B lymphocytes in vitro
(
- Contribution to journal › Article
-
Mark
Stimulation of χ transcription by a decamer‐dependent, synergistic mechanism
(
- Contribution to journal › Article
-
Mark
Pentadecamer-binding proteins : Definition of two independent protein-binding sites needed for functional activity
(
- Contribution to journal › Article
- 1994
-
Mark
Superinduction of cytokine gene transcription by ciprofloxacin
(
- Contribution to journal › Article
-
Mark
Expansion of kappa + B cells during the primary immune response to 4-hydroxy-3-nitrophenyl acetate in BALB/c mice
(
- Contribution to journal › Article
-
Mark
Kinetics of somatic mutation in lymph node germinal centres
(
- Contribution to journal › Article
- 1993
-
Mark
Analysis of somatic mutation activity in multiple V kappa genes involved in the response to 2-phenyl-5-oxazolone
(
- Contribution to journal › Article
- 1992
-
Mark
Expansion, selection and mutation of antigen-specific B cells in germinal centers
(
- Contribution to journal › Scientific review