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- 2024
-
Mark
Molecular basis of the reaction mechanism of the methyltransferase HENMT1
(
- Contribution to journal › Article
-
Mark
Regulation of biological processes by ubiquitin ligases: a focus on the Pagano Lab's contribution
(
- Contribution to journal › Article
- 2023
-
Mark
Pairing structural reconstruction with catalytic competence to evaluate the mechanisms of key enzymes in the folate-mediated one-carbon pathway
(
- Contribution to journal › Scientific review
-
Mark
Editorial: Editors' showcase 202: Insights in cell growth and division
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Regulation of osteoblast to osteocyte differentiation by cyclin-dependent kinase-1
(
- Contribution to journal › Article
-
Mark
Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity
(
- Contribution to journal › Article
-
Mark
p27Kip1 Deficiency Impairs Brown Adipose Tissue Function Favouring Fat Accumulation in Mice
(
- Contribution to journal › Article
-
Mark
Proof-of-concept method to study uncharacterized methyltransferases using PRDM15
(
- Contribution to journal › Article
-
Mark
Liver-derived metabolites as signaling molecules in fatty liver disease
(
- Contribution to journal › Scientific review
-
Mark
Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk
(
- Contribution to journal › Scientific review
- 2022
-
Mark
Histidine protonation states are key in the LigI catalytic reaction mechanism
(
- Contribution to journal › Article
-
Mark
Editorial : Editor's Pick 2021: Highlights in Cell Growth and Division
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
The catalytic mechanism of the mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2)
(
- Contribution to journal › Article
- 2021
-
Mark
Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential
2021) In Oncogene(
- Contribution to journal › Scientific review
-
Mark
Protective functions of ZO-2/Tjp2 expressed in hepatocytes and cholangiocytes against liver injury and cholestasis
(
- Contribution to journal › Article
- 2020
-
Mark
Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease
(
- Contribution to journal › Article
-
Mark
Less-well known functions of cyclin/CDK complexes
(
- Contribution to journal › Scientific review
-
Mark
Remodelling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
(
- Contribution to journal › Article
-
Mark
Cell cycle regulation in NAFLD: when imbalanced metabolism limits cell division : when imbalanced metabolism limits cell division
(
- Contribution to journal › Scientific review
-
Mark
Loss of hepatocyte cell division leads to liver inflammation and fibrosis
(
- Contribution to journal › Article
-
Mark
Cyclin-dependent kinase 1 is essential for muscle regeneration and overload muscle fiber hypertrophy
(
- Contribution to journal › Article
-
Mark
A novel function for CDK2 activity at meiotic crossover sites
(
- Contribution to journal › Article
-
Mark
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis
2020) In Oncogene(
- Contribution to journal › Article
-
Mark
Cascading proton transfers are a hallmark of the catalytic mechanism of SAM-dependent methyltransferases
(
- Contribution to journal › Article
-
Mark
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
(
- Contribution to journal › Article
-
Mark
MetaboKit : a comprehensive data extraction tool for untargeted metabolomics
(
- Contribution to journal › Article
-
Mark
Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia
(
- Contribution to journal › Article
- 2019
-
Mark
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype
2019) In Cellular and Molecular Life Sciences(
- Contribution to journal › Article
-
Mark
CDK2 kinase activity is a regulator of male germ cell fate
(
- Contribution to journal › Article
-
Mark
Diverse roles for CDK-associated activity during spermatogenesis
(
- Contribution to journal › Scientific review
-
Mark
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
(
- Contribution to journal › Article
-
Mark
Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality
(
- Contribution to journal › Article
-
Mark
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
(
- Contribution to journal › Article
-
Mark
Discovery of a chemical probe for PRDM9
(
- Contribution to journal › Article
- 2018
-
Mark
Metabolic Remodeling during Liver Regeneration
(
- Contribution to journal › Article
-
Mark
Modulation of Protein-Interaction States through the Cell Cycle
(
- Contribution to journal › Article
-
Mark
Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
(
- Contribution to journal › Article
-
Mark
Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis
(
- Contribution to journal › Article
-
Mark
Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone
(
- Contribution to journal › Article
-
Mark
Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death
(
- Contribution to journal › Article
- 2017
-
Mark
CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays
(
- Contribution to journal › Article
-
Mark
Emi2 Is Essential for Mouse Spermatogenesis
(
- Contribution to journal › Article
-
Mark
Cyclin-dependent kinasedependent phosphorylation of Sox2 at serine 39 regulates neurogenesis
(
- Contribution to journal › Article
-
Mark
Cell size control – a mechanism for maintaining fitness and function
(
- Contribution to journal › Scientific review
-
Mark
MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice
(
- Contribution to journal › Article
-
Mark
Loss of cyclin-dependent kinase 2 in the pancreas links primary β-cell dysfunction to progressive depletion of β-cell mass and diabetes
(
- Contribution to journal › Article
-
Mark
Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase i independent of Cdk2 activation
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(3). p.592-597(
- Contribution to journal › Article
- 2016
-
Mark
Cdk2 catalytic activity is essential for meiotic cell division in vivo
(
- Contribution to journal › Article
-
Mark
Impairing Cohesin Smc1/3 Head Engagement Compensates for the Lack of Eco1 Function
(
- Contribution to journal › Article
-
Mark
Regulation of the Embryonic Cell Cycle During Mammalian Preimplantation Development
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan
(
- Contribution to journal › Article
-
Mark
Cyclin A2 regulates erythrocyte morphology and numbers
(
- Contribution to journal › Article
-
Mark
Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
(
- Contribution to journal › Article
-
Mark
The indispensable role of cyclin-dependent kinase 1 in skeletal development
(
- Contribution to journal › Article
-
Mark
The Speedy A, Cdk2, p27 triangle
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Quo Vadis cell growth and division?
(
- Contribution to journal › Debate/Note/Editorial
- 2015
-
Mark
A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
2015) In Proceedings of the National Academy of Sciences of the United States of America 112(49). p.15160-15165(
- Contribution to journal › Article
-
Mark
TLR3 agonist and Sorafenib combinatorial therapy promotes immune activation and controls hepatocellular carcinoma progression
(
- Contribution to journal › Article
-
Mark
Mastl/PP2A regulate Cdk1 in ooycte maturation
(
- Contribution to journal › Review (Book/Film/Exhibition/etc.)
-
Mark
MEN1 tumorigenesis in the pituitary and pancreatic islet requires CDK4 but not Cdk2
(
- Contribution to journal › Article
-
Mark
Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress
(
- Contribution to journal › Article
- 2014
-
Mark
Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II
(
- Contribution to journal › Article
-
Mark
Spy1/SpeedyA accelerates neuroblastoma
(
- Contribution to journal › Scientific review
-
Mark
Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis
(
- Contribution to journal › Article
-
Mark
P57Kip2regulates T-cell development and lymphoma
(
- Contribution to journal › Scientific review
-
Mark
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1
(
- Contribution to journal › Article
-
Mark
The complex relationship between liver cancer and the cell cycle : A story of multiple regulations
(
- Contribution to journal › Scientific review
-
Mark
p27 is regulated independently of Skp2 in the absence of Cdk2
(
- Contribution to journal › Article
-
Mark
Identification of transcriptional and metabolic programs related to mammalian cell size
(
- Contribution to journal › Article
- 2013
-
Mark
Cyclin E1 regulates hematopoietic stem cell quiescence
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Cdks, cyclins and CKIs : Roles beyond cell cycle regulation
(
- Contribution to journal › Scientific review
- 2012
-
Mark
Evolution of the Cdk-activator Speedy/RINGO in vertebrates
(
- Contribution to journal › Article
-
Mark
Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells
(
- Contribution to journal › Article
-
Mark
Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes
(
- Contribution to journal › Article
-
Mark
Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration
2012) In Proceedings of the National Academy of Sciences of the United States of America 109(10). p.3826-3831(
- Contribution to journal › Article
-
Mark
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis
(
- Contribution to journal › Article
-
Mark
When cell cycle meets development
(
- Contribution to journal › Scientific review
- 2011
-
Mark
Established and novel Cdk/Cyclin complexes regulating the cell cycle and development
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis
(
- Contribution to journal › Article
-
Mark
Cell cycle transitions and Cdk inhibition in melanoma therapy : Cyclin' through the options
(
- Contribution to journal › Debate/Note/Editorial
- 2010
-
Mark
Enforcing the Greatwall in Mitosis
(
- Contribution to journal › Scientific review
-
Mark
Down-regulation of Myc is essential for terminal erythroid maturation
(
- Contribution to journal › Article
-
Mark
Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53
(
- Contribution to journal › Article
-
Mark
Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells
(
- Contribution to journal › Article
- 2009
-
Mark
Wnt Signaling in Mitosis
(
- Contribution to journal › Scientific review
-
Mark
Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo
(
- Contribution to journal › Article
-
Mark
Genetic mouse models to investigate cell cycle regulation
(
- Contribution to journal › Scientific review
-
Mark
Mammalian cell-cycle regulation : Several cdks, numerous cyclins and diverse compensatory mechanisms
(
- Contribution to journal › Scientific review
-
Mark
A dual role of Cdk2 in DNA damage response
(
- Contribution to journal › Scientific review
-
Mark
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53
(
- Contribution to journal › Article
-
Mark
Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition
2009) In Proceedings of the National Academy of Sciences of the United States of America 106(2). p.486-491(
- Contribution to journal › Article
- 2008
-
Mark
Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
(
- Contribution to journal › Article
-
Mark
Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications
(
- Contribution to journal › Article
-
Mark
Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury
(
- Contribution to journal › Article
-
Mark
The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation
(
- Contribution to journal › Article
-
Mark
p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
(
- Contribution to journal › Article
- 2007
-
Mark
CDK2 is dispensable for adult hippocampal neurogenesis
(
- Contribution to journal › Article
-
Mark
Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zone
(
- Contribution to journal › Article
-
Mark
p27kip1 (cyclin-dependent kinase inhibitor 1B) controls ovarian development by suppressing follicle endowment and activation and promoting follicle atresia in mice
(
- Contribution to journal › Article
-
Mark
Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2
(
- Contribution to journal › Article