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- 2024
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OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
(
- Contribution to journal › Article
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Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling
2024) In Cell Reports(
- Contribution to journal › Article
- 2023
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Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint
(
- Contribution to journal › Article
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Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestations
(
- Contribution to journal › Article
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Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
(
- Contribution to journal › Article
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Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
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- Contribution to journal › Article
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Nuclear factor Y is a pervasive regulator of neuronal gene expression
(
- Contribution to journal › Article
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The molecular genetic landscape of human brain size variation
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- Contribution to journal › Article
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SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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- Contribution to journal › Article
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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
(
- Contribution to journal › Article
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Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age
(
- Contribution to journal › Article
- 2022
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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
(
- Contribution to journal › Article
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Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
(
- Contribution to journal › Article
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Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
(
- Contribution to journal › Article
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Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27
(
- Contribution to journal › Article
- 2021
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Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
(
- Contribution to journal › Article
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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
(
- Contribution to journal › Article
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TIGER : The gene expression regulatory variation landscape of human pancreatic islets
(
- Contribution to journal › Article
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Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment
(
- Contribution to journal › Article
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No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
(
- Contribution to journal › Article
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Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells
(
- Contribution to journal › Article
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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
(
- Contribution to journal › Article
- 2020
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Complete Topological Mapping of a Cellular Protein Interactome Reveals Bow-Tie Motifs as Ubiquitous Connectors of Protein Complexes
(
- Contribution to journal › Article
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CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
(
- Contribution to journal › Article
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Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
(
- Contribution to journal › Article
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Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene
(
- Contribution to journal › Article
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Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis
(
- Contribution to journal › Article
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B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches
(
- Contribution to journal › Article
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SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP
(
- Contribution to journal › Article
- 2019
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Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
(
- Contribution to journal › Article
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PDGF-B Is Required for Development of the Glymphatic System
(
- Contribution to journal › Article
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Somatosensory Cortical Neurons Decode Tactile Input Patterns and Location from Both Dominant and Non-dominant Digits
(
- Contribution to journal › Article
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hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
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Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness
(
- Contribution to journal › Article
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Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
(
- Contribution to journal › Article
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The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
(
- Contribution to journal › Article
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Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis
(
- Contribution to journal › Article
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A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion
(
- Contribution to journal › Article
- 2018
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Selective Survival of Embryos Can Explain DNA Methylation Signatures of Adverse Prenatal Environments
(
- Contribution to journal › Article
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Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming
2018) In Cell Reports(
- Contribution to journal › Article
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Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS
(
- Contribution to journal › Article
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Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
(
- Contribution to journal › Article
- 2017
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Mark
Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
(
- Contribution to journal › Article
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CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells
(
- Contribution to journal › Article
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Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes
(
- Contribution to journal › Article
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Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism
(
- Contribution to journal › Article
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Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes
(
- Contribution to journal › Article
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Comprehensive Proteomic Characterization of Ontogenic Changes in Hematopoietic Stem and Progenitor Cells
(
- Contribution to journal › Article
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Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
(
- Contribution to journal › Article
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Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors
(
- Contribution to journal › Article
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Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition
(
- Contribution to journal › Article
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TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells
(
- Contribution to journal › Article
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Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates
(
- Contribution to journal › Article
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Mark
Emi2 Is Essential for Mouse Spermatogenesis
(
- Contribution to journal › Article
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A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors
(
- Contribution to journal › Article
- 2016
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Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors.
(
- Contribution to journal › Article
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MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
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Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion
(
- Contribution to journal › Article
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Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer
(
- Contribution to journal › Article
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Glycosaminoglycan Profiling in Patients' Plasma and Urine Predicts the Occurrence of Metastatic Clear Cell Renal Cell Carcinoma
(
- Contribution to journal › Article
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Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis
(
- Contribution to journal › Article
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Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs
(
- Contribution to journal › Article
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Direct Conversion of Fibroblasts to Megakaryocyte Progenitors
(
- Contribution to journal › Article
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Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
(
- Contribution to journal › Article
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Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses
(
- Contribution to journal › Article
- 2015
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Mark
A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors.
(
- Contribution to journal › Article
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Mark
TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells.
(
- Contribution to journal › Article
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In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry.
(
- Contribution to journal › Article
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Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis.
(
- Contribution to journal › Article
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Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.
(
- Contribution to journal › Article
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Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.
(
- Contribution to journal › Article
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Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor.
(
- Contribution to journal › Article
- 2014
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Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.
(
- Contribution to journal › Article
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Dppa5 improves hematopoietic stem cell activity by reducing endoplasmic reticulum stress.
(
- Contribution to journal › Article
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Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.
(
- Contribution to journal › Article
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Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling
(
- Contribution to journal › Article
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Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
(
- Contribution to journal › Article
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A conserved proline triplet in Val-tRNA synthetase and the origin of elongation factor P
(
- Contribution to journal › Article
- 2013
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Mark
The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells
(
- Contribution to journal › Article
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FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors
(
- Contribution to journal › Article
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Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion
(
- Contribution to journal › Article
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H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation
(
- Contribution to journal › Article
- 2012
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Mark
Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions.
(
- Contribution to journal › Article
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Mark
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
(
- Contribution to journal › Article