Diabetes - Epigenetics
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- 2024
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Mark
Achieving efficient clonal beta cells transfection using nanostraw/nanopore-assisted electroporation
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- Contribution to journal › Article
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MicroRNA 29 modulates β-cell mitochondrial metabolism and insulin secretion via underlying miR-29-OXPHOS complex pathways
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- Contribution to journal › Article
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Mark
The Impact of Our Lifestyle on the Epigenome and Metabolism
2024) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Monitoring the Intracellular Fate of Molecular Beacons : The Challenge of False Positive Signals
2024) In Advanced NanoBiomed Research(
- Contribution to journal › Article
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Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS
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- Contribution to journal › Article
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Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets
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- Contribution to journal › Article
- 2023
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Mark
Epigenetics and Obesity
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- Chapter in Book/Report/Conference proceeding › Book chapter
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Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes
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- Contribution to journal › Article
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DNA methylation partially mediates antidiabetic effects of metformin on HbA1c levels in individuals with type 2 diabetes
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- Contribution to journal › Article
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Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells
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- Contribution to journal › Article
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Salt-inducible kinases are required for glucose uptake and insulin signaling in human adipocytes
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- Contribution to journal › Article
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Circulating triglycerides are associated with human adipose tissue DNA methylation of genes linked to metabolic disease
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- Contribution to journal › Article
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Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics
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- Contribution to journal › Article
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Effect of a 3-year lifestyle intervention on telomere length in participants from PREDIMED-Plus : A randomized trial
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- Contribution to journal › Article
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Liver saturated fat content associates with hepatic DNA methylation in obese individuals
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- Contribution to journal › Article
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Mark
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
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- Contribution to journal › Article
- 2022
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Mark
Pharmacoepigenetics in type 2 diabetes : is it clinically relevant?
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- Contribution to journal › Debate/Note/Editorial
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The highly expressed calcium-insensitive synaptotagmin-11 and synaptotagmin-13 modulate insulin secretion
(
- Contribution to journal › Article
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Type 2 diabetes classification : a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
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- Contribution to journal › Article
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Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
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- Contribution to journal › Article
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Increased risk of Graves´ophthalmopathy in patients with increasing TRAb after radioiodine treatment and the impact of CTLA4 on TRAb titres
(
- Contribution to journal › Article
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Mark
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
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- Contribution to journal › Article
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Mark
Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?
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- Contribution to journal › Scientific review
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Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns, Which Associate With Future Diabetic Complications
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- Contribution to journal › Article
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Glucocorticoids and glucolipotoxicity alter the DNA methylome and function of human EndoC-βH1 cells
(
- Contribution to journal › Article
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Ex vivo and in vivo experimental investigation of miR-148a-3p as a novel therapy for insulin secretion and type 2 diabetes
2022) EASD, European Association for the Study of Diabetes, 58th annual meeting, In Diabetologia 65(Suppl 1).(
- Contribution to journal › Published meeting abstract
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Mark
Epigenetic epidemiology and alterations in type 2 diabetes and obesity
2022) p.445-474(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2021
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Mark
Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids
(
- Contribution to journal › Article
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Mark
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes : Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S
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- Contribution to journal › Article
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Mark
Excess of glucocorticoids during late gestation impairs the recovery of offspring’s β-cell function after a postnatal injury
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- Contribution to journal › Article
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Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation, Which Associates With Body Composition in the Offspring
(
- Contribution to journal › Article
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Mark
VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
(
- Contribution to journal › Article
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Mark
Statin therapy is associated with epigenetic modifications in individuals with Type 2 diabetes
(
- Contribution to journal › Article
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Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
Novel miR-29 mitochondrial-associated gene pathways predicted to regulate beta cell insulin secretion
2021) European Association for the Study of Diabetes (EASD) 57th Annual meeting In Diabetologia 64(Suppl 1).(
- Contribution to journal › Published meeting abstract
- 2020
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Mark
Epigenome- and Transcriptome-wide Changes in Muscle Stem Cells from Low Birth Weight Men
(
- Contribution to journal › Article
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Mark
Electroacupuncture mimics exercise-induced changes in skeletal muscle gene expression in women with polycystic ovary syndrome
(
- Contribution to journal › Article
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Mark
Mediterranean Diet and Telomere Length : A Systematic Review and Meta-Analysis
(
- Contribution to journal › Scientific review
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Mark
Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes
(
- Contribution to journal › Article
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Mark
Epigenetic changes in islets of langerhans preceding the onset of diabetes
(
- Contribution to journal › Article
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Mark
No symphony without bassoon and piccolo : Changes in synaptic active zone proteins in Huntington's disease
(
- Contribution to journal › Article
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Mark
Epigenetic regulation of insulin action and secretion – role in the pathogenesis of type 2 diabetes
(
- Contribution to journal › Scientific review
- 2019
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Mark
Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
(
- Contribution to journal › Article
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Mark
Liver DNA methylation of FADS2 associates with FADS2 genotypex 06 Biological Sciences 0604 Genetics
(
- Contribution to journal › Article
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Mark
Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
(
- Contribution to journal › Article
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Mark
Epigenetics in Human Obesity and Type 2 Diabetes
(
- Contribution to journal › Scientific review
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Mark
Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets
(
- Contribution to journal › Article
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Mark
Fasting unmasks differential fat and muscle transcriptional regulation of metabolic gene sets in low versus normal birth weight men
(
- Contribution to journal › Article
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Mark
The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis
(
- Contribution to journal › Article
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Mark
Epigenome-wide association study of incident type 2 diabetes in a British population : EPIC-Norfolk study
(
- Contribution to journal › Article
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Low-Dose Oral Ketamine for Procedural Analgesia in Pediatric Cancer Patients Undergoing Lumbar Puncture at a Resource-Limited Cancer Hospital in India
(
- Contribution to journal › Article
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Mark
ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.
(
- Contribution to journal › Article
- 2018
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Mark
Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children
(
- Contribution to journal › Article
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Mark
Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels
(
- Contribution to journal › Article
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Mark
DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
(
- Thesis › Doctoral thesis (compilation)
-
Mark
MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation
(
- Contribution to journal › Article
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Mark
A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome
(
- Contribution to journal › Article
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Mark
Serum and gene expression levels of CT-1, IL-6, and TNF-α after a lifestyle intervention in obese children
(
- Contribution to journal › Article
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Mark
DNA methylation in the pathogenesis of type 2 diabetes in humans
(
- Contribution to journal › Scientific review
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Mark
Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
(
- Contribution to journal › Article
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Mark
The effects of high glucose exposure on global gene expression and DNA methylation in human pancreatic islets
(
- Contribution to journal › Article
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Mark
Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary Syndrome
(
- Contribution to journal › Article
- 2017
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Mark
36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner
(
- Contribution to journal › Article
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Mark
Fetal hyperglycemia changes human preadipocyte function in adult life
(
- Contribution to journal › Article
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Mark
Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
(
- Contribution to journal › Article
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Mark
Serum oxidized low-density lipoprotein levels are related to cardiometabolic risk and decreased after a weight loss treatment in obese children and adolescents
(
- Contribution to journal › Article
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Mark
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity
(
- Contribution to journal › Article
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Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
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- Contribution to journal › Article
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HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
(
- Contribution to journal › Article
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Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver
(
- Contribution to journal › Article
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Hepatic DPP4 DNA methylation associates with fatty liver
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- Contribution to journal › Article
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Mark
Role of dietary pattern and obesity on telomere homeostasis
2017) p.133-148(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue : A randomized controlled trial
(
- Contribution to journal › Article
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Mark
Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver
(
- Contribution to journal › Article
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Mark
DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes
(
- Contribution to journal › Scientific review
- 2016
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Mark
The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes
(
- Thesis › Doctoral thesis (compilation)
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Mark
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
(
- Contribution to journal › Article
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Mark
A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
(
- Contribution to journal › Article
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Mark
Epigenetic markers to further understand insulin resistance
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Genome-wide analysis of the DNA methylation landscape in human tissues
2016)(
- Thesis › Doctoral thesis (compilation)
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Mark
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
Epigenetic programming of adipose-derived stem cells in low birthweight individuals
(
- Contribution to journal › Article
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Mark
DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk
(
- Contribution to journal › Article
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Mark
Risk för typ 2-diabetes kunde förutspås med epigenetik
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes
(
- Contribution to journal › Article
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Mark
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
(
- Contribution to journal › Article
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Mark
Developmental programming : State-of-the-science and future directions: Summary from a Pennington Biomedical symposium
(
- Contribution to journal › Scientific review
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Mark
Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
(
- Contribution to journal › Article
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Mark
NIH working group report-using genomic information to guide weight management: From universal to precision treatment.
(
- Contribution to journal › Scientific review
- 2015
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Mark
Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
(
- Contribution to journal › Article
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Mark
The potential use of DNA methylation biomarkers to identify risk and progression of type 2 diabetes.
(
- Contribution to journal › Scientific review
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Mark
Study of DNA methylation in human pancreatic islets
(
- Thesis › Doctoral thesis (compilation)
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Mark
Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?
(
- Contribution to journal › Scientific review
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Mark
Helsinki alert of biodiversity and health
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- Contribution to journal › Scientific review
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Mark
Less pronounced response to exercise in healthy relatives to type 2 diabetics compared to controls.
(
- Contribution to journal › Article
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Mark
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
(
- Contribution to journal › Article
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Mark
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
(
- Contribution to journal › Article
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Mark
DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes.
(
- Contribution to journal › Scientific review
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Mark
Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.
(
- Contribution to journal › Article
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Mark
lobChIP: from cells to sequencing ready ChIP libraries in a single day.
(
- Contribution to journal › Article