Laboratory for Experimental Brain Research
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- 2024
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Neutralization of Interleukin 1-beta is associated with preservation of thalamic capillaries after experimental traumatic brain injury
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- Contribution to journal › Article
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Impaired oligodendrogenesis in the white matter of aged mice following diffuse traumatic brain injury
2024) In GLIA(
- Contribution to journal › Article
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Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity
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- Contribution to journal › Article
- 2023
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Cerebrospinal fluid levels of neuroinflammatory biomarkers are increased in athletes with persistent post-concussive symptoms following sports-related concussion
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- Contribution to journal › Article
- 2022
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Diffuse Traumatic Injury in the Mouse Disrupts Axon-Myelin Integrity in the Cerebellum
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- Contribution to journal › Article
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Crosstalk Between GABAergic Neurotransmission and Inflammatory Cascades in the Post-ischemic Brain : Relevance for Stroke Recovery
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- Contribution to journal › Scientific review
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Intracerebral Proinflammatory Cytokine Increase in Surgically Evacuated Intracerebral Hemorrhage : A Microdialysis Study
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- Contribution to journal › Article
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A Novel In Vivo Model for Multiplexed Analysis of Callosal Connections upon Cortical Damage
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- Contribution to journal › Article
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Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke
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- Contribution to journal › Article
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RGS5 : a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes
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- Contribution to journal › Article
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Purkinje cell vulnerability induced by diffuse traumatic brain injury is linked to disruption of long-range neuronal circuits
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- Contribution to journal › Article
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Antimuscarinic-Induced Convulsions in Fasted Rats after Food Intake : EEG Patterns of Fasting, Scopolamine Treatment, and Convulsions
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- Contribution to journal › Article
- 2021
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Effect of Anti-inflammatory Treatment with AMD3100 and CX3CR1 Deficiency on GABAA Receptor Subunit and Expression of Glutamate Decarboxylase Isoforms After Stroke
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- Contribution to journal › Article
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Plasticity-enhancing effects of levodopa treatment after stroke
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- Contribution to journal › Article
- 2020
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Enhanced functional recovery by levodopa is associated with decreased levels of synaptogyrin following stroke in aged mice
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- Contribution to journal › Article
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Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling
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- Contribution to journal › Article
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Mark
Interleukin-1 beta neutralization attenuates traumatic brain injury-induced microglia activation and neuronal changes in the globus pallidus
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- Contribution to journal › Article
- 2019
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Mark
Thyroid Hormones in the Brain and Their Impact in Recovery Mechanisms After Stroke
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- Contribution to journal › Scientific review
- 2017
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GISCOME – Genetics of Ischaemic Stroke Functional Outcome network : A protocol for an international multicentre genetic association study
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- Contribution to journal › Article
- 2000
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Mark
Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons
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- Contribution to journal › Article
- 1999
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Mark
Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons
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- Contribution to journal › Article
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Rapid decline in protein kinase Cγ levels in the synaptosomal fraction of rat hippocampus after ischemic preconditioning
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- Contribution to journal › Article
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Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance
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- Contribution to journal › Article
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Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning
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- Contribution to journal › Article
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Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability
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- Contribution to journal › Article
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Activation of p53 and its target genes p21(WAF1/Cip1) and PAG608/Wig-1 in ischemic preconditioning
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- Contribution to journal › Article
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Acidosis enhances translocation of protein kinase C but not Ca2+/calmodulin-dependent protein kinase II to cell membranes during complete cerebral ischemia
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- Contribution to journal › Article
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A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence
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- Contribution to journal › Article
- 1996
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Mark
Increased Levels of Glutamate in Patients with Subarachnoid Haemorrhage as Measured by Intracerebral Microdialysis
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- Chapter in Book/Report/Conference proceeding › Chapter in report
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The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain
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- Contribution to journal › Article
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Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage
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- Contribution to journal › Article
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Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug : Evidence for chronic encephalopathic processes following ischemia
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- Contribution to journal › Article
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Mark
Intracellular signal transduction in the postischemic brain.
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- Contribution to journal › Scientific review
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The effect of hypothermia on protein synthesis and the expression of immediate early genes following transient cerebral ischemia.
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- Contribution to journal › Article
- 1995
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Mark
Alterations of Ca2+/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia
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- Contribution to journal › Article
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Mark
Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia
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- Contribution to journal › Article
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Mark
Persistent Translocation of Ca2+/Calmodulin‐Dependent Protein Kinase II to Synaptic Junctions in the Vulnerable Hippocampal CA1 Region Following Transient Ischemia
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- Contribution to journal › Article
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Mark
Persistent Translocation and Inhibition of Ca2+/Calmodulin‐Dependent Protein Kinase II in the Crude Synaptosomal Fraction of the Vulnerable Hippocampus Following Hypoglycemia
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- Contribution to journal › Article
- 1994
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Mark
Tyrosine Phosphorylation and Activation of Mitogen‐ Activated Protein Kinase in the Rat Brain Following Transient Cerebral Ischemia
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- Contribution to journal › Article
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Mark
Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia
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- Contribution to journal › Article
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Mark
Changes in the Tyrosine Phosphorylation of Mitogen‐Activated Protein Kinase in the Rat Hippocampus During and Following Severe Hypoglycemia
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- Contribution to journal › Debate/Note/Editorial
- 1993
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Mark
Protein phosphorylation and the regulation of mRNA translation following cerebral ischemia
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- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Postischaemic changes in protein synthesis in the rat brain : effects of hypothermia
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- Contribution to journal › Article
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Heat-shock inhibits protein synthesis and eIF-2 activity in cultured cortical neurons
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- Contribution to journal › Article
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Casein Kinase II Activity in the Postischemic Rat Brain Increases in Brain Regions Resistant to Ischemia and Decreases in Vulnerable Areas
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- Contribution to journal › Article
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Mark
Depression of Neuronal Protein Synthesis Initiation by Protein Tyrosine Kinase Inhibitors
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- Contribution to journal › Article
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Mark
Initiation of protein synthesis and heat-shock protein-72 expression in the rat brain following severe insulin-induced hypoglycemia
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- Contribution to journal › Article
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Stress-induced inhibition of protein synthesis initiation : Modulation of initiation factor 2 and guanine nucleotide exchange factor activities following transient cerebral ischemia in the rat
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- Contribution to journal › Article
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Mark
Ischemia-induced upregulation of excitatory amino acid transport sites
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- Contribution to journal › Article
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Mark
Time Course of the Translocation and Inhibition of Protein kinase C During Complete Cerebral Ischemia in the Rat
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- Contribution to journal › Article
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Mark
Changes in tyrosine phosphorylation in neocortex following transient cerebral ischaemia
(
- Contribution to journal › Article
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Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat : Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1
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- Contribution to journal › Article
- 1992
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Mark
Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia
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- Contribution to journal › Article
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Mark
NMDA‐receptor blockers but not NBQX, an AMPA‐receptor antagonist, inhibit spreading depression in the rat brain
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- Contribution to journal › Article
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Brain cortical tissue levels of noradrenaline and its glycol metabolites : effects of ischemia and postischemic administration of idazoxan
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- Contribution to journal › Article
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Hypothermia ameliorates neuronal survival when induced 2 hours after ischaemia in the rat
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- Contribution to journal › Article
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Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia : evidence against programmed cell death
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- Contribution to journal › Article
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Mark
Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia
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- Contribution to journal › Article
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Mark
Effects of ischemia on regional ligand binding to adrenoceptors in the rat brain
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- Contribution to journal › Article
- 1991
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Mark
Changes in the Activity of Protein Kinase C and the Differential Subcellular Redistribution of Its Isozymes in the Rat Striatum During and Following Transient Forebrain Ischemia
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- Contribution to journal › Article
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Mark
Lack of protection by the N-methyl-D-asparate receptor blocker dizocilpine (MK-801) after transient severe cerebral ischemia in the rat
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- Contribution to journal › Article
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Mark
Changes in pyruvate dehydrogenase complex activity during and following severe insulin-induced hypoglycemia
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- Contribution to journal › Article
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Mark
Extracellular brain cortical levels of noradrenaline in ischemia : - Effects of desipramine and postischemic administration of idazoxan
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- Contribution to journal › Article
- 1990
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Mark
Neuronal damage in the striatum following forebrain ischemia : lack of effect of selective lesions of mesostriatal dopamine neurons
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- Contribution to journal › Article
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Neuronal injury and cerebrovascular disorders
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- Contribution to journal › Scientific review
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Preischemic hyperglycemia and postischemic alteration of rat brain pyruvate dehydrogenase activity
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- Contribution to journal › Article
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Extracellular levels of quinolinic acid are moderately increased in rat neostriatum following severe insulin-induced hypoglycaemia
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- Contribution to journal › Article
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Influence of MK-801 on brain extracellular calcium and potassium activities in severe hypoglycemia
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- Contribution to journal › Article
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Cortical spreading depression is associated with arachidonic acid accumulation and preservation of energy charge
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- Contribution to journal › Article
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Protection against ischemia-induced neuronal damage by the α2-adrenoceptor antagonist idazoxan : influence of time of administration and possible mechanisms of action
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- Contribution to journal › Article
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Mark
Protein kinase C is translocated to cell membranes during cerebral ischemia
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- Contribution to journal › Article
- 1989
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Mark
Noradrenaline Metabolism in Neocortex and Hippocampus Following Transient Forebrain Ischemia in Rats : Relation to Development of Selective Neuronal Necrosis
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- Contribution to journal › Article
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Mark
Pyruvate dehydrogenase activity in the rat cerebral cortex following cerebral ischemia
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- Contribution to journal › Article
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Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia
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- Contribution to journal › Article
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Changes in Excitatory Amino Acid Receptor Binding in the Intact and Decorticated Rat Neostriatum Following Insulin‐Induced Hypoglycemia
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- Contribution to journal › Article
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Mark
Impairment of protein ubiquitination may cause delayed neuronal death
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- Contribution to journal › Article
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Mark
Postischemic administration of idazoxan, an α-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain
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- Contribution to journal › Article
- 1988
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Mark
The NMDA-antagonist MK-801 reduces extracellular amino acid levels during hypoglycemia and prevents striatal damage
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- Contribution to journal › Article
- 1987
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Mark
Protective effect of lesion to the glutamatergic cortico-striatal projections on the hypoglycemic nerve cell injury in rat striatum
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- Contribution to journal › Article
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Mark
Excitatory amino acid receptors and ischemic brain damage in the rat
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- Contribution to journal › Article
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Regional differences in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia
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- Contribution to journal › Article
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Mark
Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia
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- Contribution to journal › Article
- 1986
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Mark
Effect of Insulin‐Induced Hypoglycemia on the Concentrations of Glutamate and Related Amino Acids and Energy Metabolites in the Intact and Decorticated Rat Neostriatum
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- Contribution to journal › Article
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Mark
Circulating catecholamines modulate ischemic brain damage
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- Contribution to journal › Article
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Mark
Lesions to the Corticostriatal Pathways Ameliorate Hypoglycemia‐Induced Arachidonic Acid Release
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- Contribution to journal › Article
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Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage.
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- Contribution to journal › Article
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Mark
Flunarizine, a calcium entry blocker, ameliorates ischemic brain damage in the rat
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- Contribution to journal › Article
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Mark
The effect of isoflurane on neuronal necrosis following near-complete forebrain ischemia in the rat
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- Contribution to journal › Article
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Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis
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- Contribution to journal › Article
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Mark
Epileptic brain damage : pathophysiology and neurochemical pathology.
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- Contribution to journal › Scientific review
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Mark
Cellular and Molecular Events Underlying Epileptic Brain Damage
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- Contribution to journal › Article
- 1985
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Mark
Neurochemical Correlates to Selective Neuronal Vulnerability
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- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Cerebral metabolism in ischaemia : Neurochemical basis for therapy
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- Contribution to journal › Article
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Ischemic brain damage in rats following cardiac arrest using a long-term recovery model
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- Contribution to journal › Article
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Amelioration of ischaemic brain damage by postischaemic treatment with flunarizine
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- Contribution to journal › Article
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Mark
Influence of acidosis on lipid peroxidation in brain tissues in vitro
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- Contribution to journal › Article
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Mark
Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path
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- Contribution to journal › Article
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Mark
Cyclic AMP Concentrations in Rat Neocortex and Hippocampus During and Following Incomplete Ischemia : Effects of Central Noradrenergic Neurons, Prostaglandins, and Adenosine
(
- Contribution to journal › Article
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Mark
The dentate gyrus in hypoglycemia : Pathology implicating excititoxin-mediated neuronal necrosis
(
- Contribution to journal › Article
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Mark
Trypsin activation of porcine procolipase. Kinetics of activation and effects on lipid binding
(
- Contribution to journal › Article