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- 2023
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Mark
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β
(
- Contribution to journal › Article
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Mark
Cerebral Aβ deposition precedes reduced cerebrospinal fluid and serum Aβ42/Aβ40 ratios in the App NL−F/NL−F knock-in mouse model of Alzheimer’s disease
(
- Contribution to journal › Article
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Mark
Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice
(
- Contribution to journal › Article
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Mark
Fluorescently Guided Optical Photothermal Infrared Microspectroscopy for Protein-Specific Bioimaging at Subcellular Level
(
- Contribution to journal › Article
-
Mark
Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis
(
- Contribution to journal › Article
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Mark
Apolipoprotein E intersects with amyloid-β within neurons
(
- Contribution to journal › Article
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Mark
Intracellular Amyloid-β in the Normal Rat Brain and Human Subjects and Its relevance for Alzheimer's Disease
(
- Contribution to journal › Article
- 2022
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Mark
APOE in the bullseye of neurodegenerative diseases : impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
(
- Contribution to journal › Scientific review
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Mark
Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
(
- Contribution to journal › Article
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Mark
Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture
(
- Contribution to journal › Article
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Mark
Correlative imaging to resolve molecular structures in individual cells: Substrate validation study for super-resolution infrared microspectroscopy
(
- Contribution to journal › Article
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Mark
Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer’s Disease
(
- Contribution to journal › Article
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Mark
Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease
2022) In Acta Neuropathologica(
- Contribution to journal › Article
-
Mark
Aβ/APP-induced hyperexcitability and dysregulation of homeostatic synaptic plasticity in models of Alzheimer’s disease
2022)(
- Working paper/Preprint › Preprint in preprint archive
-
Mark
Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties
(
- Contribution to journal › Article
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Mark
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
(
- Contribution to journal › Article
- 2021
-
Mark
Neuronal α-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology
(
- Contribution to journal › Article
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Mark
FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation
(
- Contribution to journal › Article
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Mark
Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis
(
- Contribution to journal › Article
-
Mark
Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease
(
- Contribution to journal › Article
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Mark
APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis
(
- Contribution to journal › Article
-
Mark
In memoriam for M. Flint Beal
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
DNAJB6b is Downregulated in Synucleinopathies
(
- Contribution to journal › Article
-
Mark
Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains
(
- Contribution to journal › Article
-
Mark
Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions
(
- Contribution to journal › Article
-
Mark
Neurobiological role of Alzheimer's disease genetic risk factor ApoE on early synaptic changes in Alzheimer-like models
(
- Contribution to journal › Published meeting abstract
-
Mark
Nano-Infrared Imaging of Primary Neurons
(
- Contribution to journal › Article
-
Mark
Astrocytic and Neuronal Apolipoprotein E Isoforms Differentially Affect Neuronal Excitability
(
- Contribution to journal › Article
-
Mark
Up-regulation of APP endocytosis by neuronal aging drives amyloid dependent-synapse loss
(
- Contribution to journal › Article
-
Mark
Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
(
- Contribution to journal › Article
- 2020
-
Mark
Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons
2020) In Advanced Science(
- Contribution to journal › Article
-
Mark
Human iPSC-Derived Hippocampal Spheroids : An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies
(
- Contribution to journal › Article
- 2019
-
Mark
Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection.
(
- Contribution to journal › Article
-
Mark
APP depletion alters selective pre- and post-synaptic proteins
(
- Contribution to journal › Article
-
Mark
Aging, metabolism, synaptic activity, and Aβ in Alzheimer's disease
(
- Contribution to journal › Debate/Note/Editorial
- 2018
-
Mark
S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease
(
- Contribution to journal › Article
-
Mark
Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice
2018) 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 2018-September.(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Prion-like seeding and nucleation of intracellular amyloid-β
(
- Contribution to journal › Article
- 2017
-
Mark
Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease
(
- Contribution to journal › Scientific review
-
Mark
Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A
(
- Contribution to journal › Article
-
Mark
Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses
(
- Contribution to journal › Article
-
Mark
Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP
(
- Contribution to journal › Article
- 2016
-
Mark
Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease
(
- Contribution to journal › Article
-
Mark
Brain activity and Alzheimer's disease : A complex relationship
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease?
(
- Contribution to journal › Article
- 2015
-
Mark
β-amyloid Peptides and Amyloid Plaques in Alzheimer's Disease.
(
- Contribution to journal › Scientific review
-
Mark
ADAM10 and BACE1 are localized to synaptic vesicles.
(
- Contribution to journal › Article
- 2014
-
Mark
Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.
(
- Contribution to journal › Article
-
Mark
Activity-independent release of the amyloid β-peptide from rat brain nerve terminals.
(
- Contribution to journal › Article
-
Mark
Detection of pre-plaque amyloid aggregation using FTIR
(
- Contribution to journal › Article
-
Mark
The Inside-Out Amyloid Hypothesis and Synapse Pathology in Alzheimer's Disease.
(
- Contribution to journal › Article
- 2013
-
Mark
Nonsteroidal Selective Androgen Receptor Modulators and Selective Estrogen Receptor β Agonists Moderate Cognitive Deficits and Amyloid-β Levels in a Mouse Model of Alzheimer's Disease.
(
- Contribution to journal › Article
-
Mark
Accumulation of Intraneuronal beta-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses
(
- Contribution to journal › Article
-
Mark
mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases.
(
- Contribution to journal › Scientific review
- 2012
-
Mark
Pathology of Synapses and Dendritic Spines
2012) In Journal of Neural Transplantation & Plasticity(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Intraneuronal A beta Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer's Disease
(
- Contribution to journal › Article
-
Mark
Critical role of intraneuronal A beta in Alzheimer's disease: Technical challenges in studying intracellular A beta
(
- Contribution to journal › Article
- 2011
-
Mark
Impaired β-Amyloid Secretion in Alzheimer's Disease Pathogenesis.
2011) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 31(43). p.15384-15390(
- Contribution to journal › Article
-
Mark
High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils
(
- Contribution to journal › Article
-
Mark
Analysis of vesicular trafficking in primary neurons by live imaging.
(
- Contribution to journal › Article
-
Mark
Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of alzheimer's disease
(
- Contribution to journal › Article
-
Mark
Accumulation of cellular prion protein within dystrophic neurites of amyloid plaques in the Alzheimer's disease brain
(
- Contribution to journal › Article
-
Mark
Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of CIC-7 to lysosomes
(
- Contribution to journal › Article
- 2010
-
Mark
Synapses, synaptic activity and intraneuronal Aβ in Alzheimer's disease
(
- Contribution to journal › Scientific review
-
Mark
Effects of synaptic modulation on β-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice
(
- Contribution to journal › Article
-
Mark
Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease
(
- Contribution to journal › Article
-
Mark
Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer's disease
(
- Contribution to journal › Scientific review
-
Mark
Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses
(
- Contribution to journal › Article
- 2009
-
Mark
Dementia
2009) p.403-408(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Synaptic activity reduces intraneuronal Aβ, promotes APP transport to synapses, and protects against Aβ-related synaptic alterations
(
- Contribution to journal › Article
-
Mark
Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation
(
- Contribution to journal › Article
-
Mark
Immunotherapy for Alzheimer disease
(
- Contribution to journal › Article
-
Mark
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease
(
- Contribution to journal › Article
- 2007
-
Mark
Internalized antibodies to the Aβ domain of APP reduce neuronal Aβ and protect against synaptic alterations
(
- Contribution to journal › Article
-
Mark
The Arctic Alzheimer mutation favors intracellular amyloid-β production by making amyloid precursor protein less available to α-secretase
(
- Contribution to journal › Article
-
Mark
β-amyloid modulation of synaptic transmission and plasticity
(
- Contribution to journal › Article
-
Mark
Alzheimer's disease therapy : Focus on synapses
(
- Contribution to journal › Debate/Note/Editorial
- 2006
-
Mark
β-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system
(
- Contribution to journal › Article
-
Mark
Neurogenesis as a therapeutic strategy for cognitive aging and Alzheimer's disease
(
- Contribution to journal › Article
- 2005
-
Mark
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
(
- Contribution to journal › Article
-
Mark
Regulation of NMDA receptor trafficking by amyloid-β
(
- Contribution to journal › Article
-
Mark
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
(
- Contribution to journal › Scientific review
-
Mark
Intraneuronal β-amyloid expression downregulates the Akt survival pathway and blunts the stress response
(
- Contribution to journal › Article
-
Mark
Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice
(
- Contribution to journal › Article
-
Mark
Amyloid-β oligomers are inefficiently measured by enzyme-linked immunosorbent assay
(
- Contribution to journal › Article
-
Mark
The immune system, amyloid-β peptide, and Alzheimer's disease
(
- Contribution to journal › Scientific review
- 2004
-
Mark
Immunocytochemical analysis of amyloid precursor protein and its derivatives
2004) p.155-164(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
(
- Contribution to journal › Article
-
Mark
Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain
(
- Contribution to journal › Article
-
Mark
Intraneuronal Aβ accumulation-more evidence, less controversy? Alzheimer research forum live discussion
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Axonal transport hypothesis moves on to implicate presenilin : Alzheimer research forum live discussion
(
- Contribution to journal › Debate/Note/Editorial
- 2003
-
Mark
Chaperones increase association of tau protein with microtubules
2003) In Proceedings of the National Academy of Sciences of the United States of America 100(2). p.721-726(
- Contribution to journal › Article
-
Mark
Live discussion : From here to there: AβPP as an axonal transport receptor - How could this explain neurodegeneration in AD?
(
- Contribution to journal › Debate/Note/Editorial
- 2002
-
Mark
Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
(
- Contribution to journal › Article
-
Mark
Alzheimer β-amyloid peptides : Normal and abnormal localization
(
- Contribution to journal › Scientific review
- 2001
-
Mark
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
(
- Contribution to journal › Article
-
Mark
Current theories for the molecular and cellular pathogenesis of Alzheimer's disease
(
- Contribution to journal › Article
-
Mark
Metal chelator decreases alzheimer β-amyloid plaques
(
- Contribution to journal › Scientific review
- 2000
-
Mark
Intraneuronal Aβ42 accumulation in human brain
(
- Contribution to journal › Article