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- 2024
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Mark
Modular 3D printed platform for fluidically connected human brain organoid culture
(
- Contribution to journal › Article
-
Mark
The history and status of dopamine cell therapies for Parkinson's disease
2024) In BioEssays(
- Contribution to journal › Scientific review
- 2023
-
Mark
Athymic Nude Rat Brain Atlas
2023)(
- Book/Report › Book
-
Mark
hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum
(
- Contribution to journal › Article
-
Mark
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants
in vivo.
(
- Contribution to journal › Article
-
Mark
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
(
- Contribution to journal › Article
-
Mark
In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids
(
- Contribution to journal › Article
-
Mark
Protocol for optical clearing and imaging of fluorescently labeled ex vivo rat brain slices
(
- Contribution to journal › Article
- 2022
-
Mark
A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
(
- Contribution to journal › Article
-
Mark
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
(
- Contribution to journal › Article
-
Mark
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease
(
- Contribution to journal › Article
-
Mark
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
(
- Contribution to journal › Scientific review
-
Mark
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells
(
- Contribution to journal › Article
-
Mark
Silk scaffolding drives self-assembly of functional and mature human brain organoids
(
- Contribution to journal › Article
-
Mark
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
(
- Contribution to journal › Article
-
Mark
Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs
(
- Contribution to journal › Article
-
Mark
Targets for astrocyte-based treatments of Parkinson's disease (PD)
(
- Contribution to journal › Article
-
Mark
Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia
(
- Contribution to journal › Article
-
Mark
Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery
(
- Contribution to journal › Article
- 2021
-
Mark
Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation
(
- Contribution to journal › Article
-
Mark
Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons
(
- Contribution to journal › Article
-
Mark
Neural tube patterning : from a minimal model for rostrocaudal patterning toward an integrated 3D model
(
- Contribution to journal › Article
-
Mark
3D biomaterial models of human brain disease
(
- Contribution to journal › Article
-
Mark
Dopamine Cell Therapy : From Cell Replacement to Circuitry Repair
(
- Contribution to journal › Scientific review
-
Mark
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Dopamine Neuron Diversity : Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing
(
- Contribution to journal › Scientific review
-
Mark
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
(
- Contribution to journal › Scientific review
-
Mark
Reprogramming Stars #4 : A Reprogramming Approach for Parkinson's Disease-An Interview with Dr. Malin Parmar
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
(
- Contribution to journal › Article
- 2020
-
Mark
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits
(
- Contribution to journal › Article
-
Mark
The future of stem cell therapies for Parkinson disease
(
- Contribution to journal › Scientific review
-
Mark
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells
(
- Contribution to journal › Article
-
Mark
From Skin to Brain : A Parkinson's Disease Patient Transplanted with His Own Cells
(
- Contribution to journal › Article
-
Mark
3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices
(
- Contribution to journal › Article
-
Mark
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair : 40 Years in Perspective
(
- Contribution to journal › Scientific review
-
Mark
Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(16). p.9094-9100(
- Contribution to journal › Article
-
Mark
Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons
(
- Contribution to journal › Article
-
Mark
Parkinson’s disease laterality : a 11C-PE2I PET imaging study
2020) In Journal of Neurology(
- Contribution to journal › Article
-
Mark
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease
(
- Contribution to journal › Article
-
Mark
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
(
- Contribution to journal › Article
-
Mark
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(26). p.15209-15220(
- Contribution to journal › Article
- 2019
-
Mark
Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force
(
- Contribution to journal › Article
-
Mark
Advances in stem cell research and therapeutic development
(
- Contribution to journal › Scientific review
-
Mark
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
(
- Contribution to journal › Article
-
Mark
Stem cell culture conditions and stability : a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform
(
- Contribution to journal › Article
-
Mark
Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons
(
- Contribution to journal › Article
-
Mark
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
2019) In Proceedings of the National Academy of Sciences of the United States of America 116(52). p.27053-27062(
- Contribution to journal › Article
-
Mark
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease
(
- Contribution to journal › Article
- 2018
-
Mark
Developing defined substrates for stem cell culture and differentiation
(
- Contribution to journal › Scientific review
-
Mark
Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts
(
- Contribution to journal › Article
-
Mark
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
(
- Contribution to journal › Article
-
Mark
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
(
- Contribution to journal › Article
-
Mark
Towards stem cell based therapies for parkinson’s disease
(
- Contribution to journal › Article
-
Mark
New approaches for brain repair-from rescue to reprogramming
(
- Contribution to journal › Scientific review
-
Mark
Repairing the brain : Cell replacement using stem cell-based technologies
(
- Contribution to journal › Scientific review
-
Mark
Women in Stem Cell Science: Part I
(
- Contribution to journal › Debate/Note/Editorial
- 2017
-
Mark
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells
(
- Contribution to journal › Article
-
Mark
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation
(
- Contribution to journal › Article
-
Mark
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model
(
- Contribution to journal › Letter
-
Mark
Term amniotic fluid : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications
(
- Contribution to journal › Article
-
Mark
Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
(
- Contribution to journal › Article
-
Mark
Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages
(
- Contribution to journal › Article
-
Mark
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells
(
- Contribution to journal › Article
-
Mark
REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways
(
- Contribution to journal › Article
-
Mark
Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease : Dawn of a New Era
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming
(
- Contribution to journal › Article
-
Mark
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli
(
- Contribution to journal › Article
-
Mark
Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
(
- Contribution to journal › Article
-
Mark
Direct neuronal reprogramming for disease modeling studies using patient-derived neurons : What have we learned?
(
- Contribution to journal › Scientific review
-
Mark
Strategies for bringing stem cell-derived dopamine neurons to the clinic : A European approach (STEM-PD)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
GFORCE-PD still going strong in 2016
(
- Contribution to journal › Scientific review
- 2016
-
Mark
Plug and Play Brain : Understanding Integration of Transplanted Neurons for Brain Repair
(
- Contribution to journal › Article
-
Mark
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
(
- Contribution to journal › Article
-
Mark
HESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
(
- Contribution to journal › Article
-
Mark
Comparability : Manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015
(
- Contribution to journal › Article
-
Mark
Brain repair and reprogramming : the route to clinical translation
(
- Contribution to journal › Scientific review
-
Mark
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
(
- Contribution to journal › Article
-
Mark
Small molecules increase direct neural conversion of human fibroblasts
(
- Contribution to journal › Article
-
Mark
10 Questions : Clinical Outlook for iPSCs
(
- Contribution to journal › Debate/Note/Editorial
- 2015
-
Mark
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
(
- Contribution to journal › Article
-
Mark
In Vivo Reprogramming for Brain and Spinal Cord Repair(1,2,3).
(
- Contribution to journal › Scientific review
-
Mark
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.
(
- Contribution to journal › Article
-
Mark
Cell-based therapies for Parkinson disease-past insights and future potential.
(
- Contribution to journal › Scientific review
-
Mark
In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry.
(
- Contribution to journal › Article
- 2014
-
Mark
Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.
(
- Contribution to journal › Article
-
Mark
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons
(
- Contribution to journal › Article
-
Mark
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation.
(
- Contribution to journal › Article
-
Mark
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
(
- Contribution to journal › Article
-
Mark
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Cell therapies for Parkinson's disease
(
- Contribution to journal › Article
- 2013
-
Mark
Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens
(
- Contribution to journal › Article
-
Mark
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.
(
- Contribution to journal › Article
-
Mark
Generation of induced neurons via direct conversion in vivo.
(
- Contribution to journal › Article
- 2012
-
Mark
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol.
(
- Contribution to journal › Article
-
Mark
Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment
(
- Contribution to journal › Article
-
Mark
Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions.
(
- Contribution to journal › Article