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- 2024
-
Mark
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
The history and status of dopamine cell therapies for Parkinson's disease
2024) In BioEssays(
- Contribution to journal › Scientific review
-
Mark
The AAV-α-Synuclein Model of Parkinson's Disease : An Update
2024) In Journal of Parkinson's Disease(
- Contribution to journal › Scientific review
- 2023
-
Mark
Athymic Nude Rat Brain Atlas
2023)(
- Book/Report › Book
-
Mark
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
(
- Contribution to journal › Article
-
Mark
Restorative cell and gene therapies for Parkinson's disease
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2022
-
Mark
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
(
- Contribution to journal › Scientific review
- 2021
-
Mark
Dopamine Cell Therapy : From Cell Replacement to Circuitry Repair
(
- Contribution to journal › Scientific review
-
Mark
Repairing the Parkinson Brain
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
(
- Contribution to journal › Scientific review
-
Mark
Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?
(
- Contribution to journal › Article
-
Mark
GDNF Therapy : Can We Make It Work?
(
- Contribution to journal › Article
- 2020
-
Mark
Preface : The evolving scenario of Parkinson's research
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits
(
- Contribution to journal › Article
-
Mark
Animal models for preclinical Parkinson´s research: An update and critical appraisal
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
From Skin to Brain : A Parkinson's Disease Patient Transplanted with His Own Cells
(
- Contribution to journal › Article
-
Mark
GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop
(
- Contribution to journal › Article
-
Mark
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair : 40 Years in Perspective
(
- Contribution to journal › Scientific review
-
Mark
Parkinson’s disease laterality : a 11C-PE2I PET imaging study
2020) In Journal of Neurology(
- Contribution to journal › Article
-
Mark
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(26). p.15209-15220(
- Contribution to journal › Article
-
Mark
BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia
(
- Contribution to journal › Article
-
Mark
Animal Models of Parkinson's Disease : Are They Useful or Not?
(
- Contribution to journal › Scientific review
- 2019
-
Mark
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
The amphetamine induced rotation test : A re-assessment of its use as a tool to monitor motor impairment and functional recovery in rodent models of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease
(
- Contribution to journal › Article
- 2018
-
Mark
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
The serotonergic system in L-DOPA-induced dyskinesia : pre-clinical evidence and clinical perspective
(
- Contribution to journal › Article
-
Mark
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
(
- Contribution to journal › Article
- 2017
-
Mark
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(39). p.8284-8293(
- Contribution to journal › Article
-
Mark
Mechanisms and use of neural transplants for brain repair
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Replacing Dopamine Neurons in Parkinson's Disease : How did it happen?
(
- Contribution to journal › Scientific review
-
Mark
BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats
(
- Contribution to journal › Article
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
- 2016
-
Mark
Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.
(
- Contribution to journal › Article
-
Mark
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
2016) In Proceedings of the National Academy of Sciences of the United States of America 113(23). p.6544-6549(
- Contribution to journal › Article
-
Mark
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
(
- Contribution to journal › Article
-
Mark
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
(
- Contribution to journal › Article
- 2015
-
Mark
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
(
- Contribution to journal › Article
-
Mark
Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.
(
- Contribution to journal › Scientific review
-
Mark
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.
(
- Contribution to journal › Article
-
Mark
GDNF is not required for catecholaminergic neuron survival in vivo.
(
- Contribution to journal › Letter
-
Mark
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.
(
- Contribution to journal › Article
-
Mark
Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.
2015) In Biological Psychiatry(
- Contribution to journal › Article
-
Mark
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
(
- Contribution to journal › Article
-
Mark
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.
(
- Contribution to journal › Article
-
Mark
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.
(
- Contribution to journal › Article
- 2014
-
Mark
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
(
- Contribution to journal › Article
-
Mark
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Long-term clinical outcome of fetal cell transplantation for Parkinson disease : two case reports
(
- Contribution to journal › Article
- 2013
-
Mark
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
TFEB: Pathogenic role and therapeutic target in Parkinson disease.
(
- Contribution to journal › Article
-
Mark
mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats
(
- Contribution to journal › Article
-
Mark
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
(
- Contribution to journal › Article
-
Mark
Trophic Factor Gene Therapy for Parkinson's Disease
(
- Contribution to journal › Scientific review
-
Mark
Cell therapy for Parkinson's disease: what next?
(
- Contribution to journal › Article
-
Mark
Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.
(
- Contribution to journal › Scientific review
-
Mark
Generation of induced neurons via direct conversion in vivo.
(
- Contribution to journal › Article
-
Mark
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
(
- Contribution to journal › Article
- 2012
-
Mark
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
(
- Contribution to journal › Article
-
Mark
Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study.
(
- Contribution to journal › Article
-
Mark
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.
(
- Contribution to journal › Article
-
Mark
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Generation of Transplantable Striatal Projection Neurons from Human ESCs.
(
- Contribution to journal › Article
-
Mark
Introduction (Part I)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Introduction (Part II)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Profile of Anders Bjorklund. Interview by Beth Azar
2012) In Proceedings of the National Academy of Sciences of the United States of America 109(33). p.9-13137(
- Contribution to journal › Article
-
Mark
Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson's Patients Treated with Dopamine Grafts
(
- Contribution to journal › Article
-
Mark
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
(
- Contribution to journal › Article
-
Mark
α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons.
(
- Contribution to journal › Article
-
Mark
Comparison of the behavioural and histological characteristics of the 6-OHDA and alpha-synuclein rat models of Parkinson's disease
(
- Contribution to journal › Article
- 2011
-
Mark
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Graft-Induced Dyskinesias in Parkinson's Disease: High Striatal Serotonin/Dopamine Transporter Ratio
(
- Contribution to journal › Article
-
Mark
Direct conversion of human fibroblasts to dopaminergic neurons.
(
- Contribution to journal › Article
-
Mark
Cell Therapeutics in Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Gene therapy for Parkinson's disease shows promise.
(
- Contribution to journal › Article
- 2010
-
Mark
Recent Advances In Parkinson'S Disease: Translational And Clinical Research Preface
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells
(
- Contribution to journal › Article
-
Mark
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Glial Cell Derived Neurotrophic Factor Does not Provide Neuroprotection Against Alpha-Synuclein-Induced Toxicity in a Rat Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
The Role of Norepinephrine Neurons in Motor Symptoms of Parkinson's Disease and Development of L-DOPA-Induced Dyskinesia
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy Body Pathology in 12-and 16-Year Old Intrastriatal Mesencephalic Grafts Surviving in a Patient with Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
(
- Contribution to journal › Article
-
Mark
Characterisation of Behavioural and Neurodegenerative Changes Induced by Intranigral 6-Hydroxydopamine Lesions in a Mouse Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
New Mouse Models for Studying Postnatal Role of GDNF In Vivo
2010) 17th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair In Cell Transplantation 19(3). p.331-331(
- Contribution to journal › Published meeting abstract
-
Mark
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
(
- Contribution to journal › Article
-
Mark
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Recent advances in Parkinson's disease : basic research. Preface
(
- Contribution to journal › Article
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia
(
- Contribution to journal › Scientific review
- 2009
-
Mark
Differential Infectivity Following Basal Ganglia Administration of Differing AAV Serotypes in Nonhuman Primates
2009) 16th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair In Cell Transplantation 18(2). p.212-213(
- Contribution to journal › Published meeting abstract
-
Mark
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
(
- Contribution to journal › Article
-
Mark
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT(1A) and 5-HT(1B) receptor agonists in the rat Parkinson model.
(
- Contribution to journal › Article
-
Mark
Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts
(
- Contribution to journal › Scientific review
-
Mark
Gene therapy for dopamine replacement in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.
(
- Contribution to journal › Article
-
Mark
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration.
(
- Contribution to journal › Article
-
Mark
Identification of Transplantable Dopamine Neuron Precursors at Different Stages of Midbrain Neurogenesis.
(
- Contribution to journal › Article
-
Mark
Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons
(
- Contribution to journal › Article
- 2008
-
Mark
Embryonic dopaminergic precursors can be isolated at different states of differentiation and function upon grafting into an animal model of Parkinson's disease
2008) 17th Biennial Meeting of the International-Society-for-Developmental-Neuroscience In International Journal of Developmental Neuroscience 26(8). p.887-888(
- Contribution to journal › Published meeting abstract
-
Mark
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway
(
- Contribution to journal › Article
-
Mark
Gene therapy for Parkinson's disease
2008) 19th Helsinki Drug Research 2008 In European Journal of Pharmaceutical Sciences 34(1, Suppl. 1). p.14-14(
- Contribution to journal › Published meeting abstract
-
Mark
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
(
- Contribution to journal › Article
-
Mark
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.
(
- Contribution to journal › Article
-
Mark
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
(
- Contribution to journal › Article
-
Mark
Involvement of the serotonin system in L-dopa-induced dyskinesias
(
- Contribution to journal › Article
-
Mark
Serotonin-dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias
(
- Contribution to journal › Article
- 2007
-
Mark
Dopamine neuron systems in the brain: an update
(
- Contribution to journal › Scientific review
-
Mark
The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease
(
- Contribution to journal › Article
-
Mark
In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.
(
- Contribution to journal › Article
-
Mark
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Fifty years of dopamine research.
(
- Contribution to journal › Letter
-
Mark
Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.
(
- Contribution to journal › Article
- 2006
-
Mark
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2.
(
- Contribution to journal › Article
-
Mark
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.
(
- Contribution to journal › Article
-
Mark
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia.
(
- Contribution to journal › Article
- 2005
-
Mark
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
(
- Contribution to journal › Article
-
Mark
Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.
(
- Contribution to journal › Article
-
Mark
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.
(
- Contribution to journal › Article
-
Mark
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors.
(
- Contribution to journal › Article
-
Mark
Parkinson's disease: Viral vector delivery of parkin generates model results in rats.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Cell transplantation in Parkinson's disease: how can we make it work?
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.
(
- Contribution to journal › Article
-
Mark
Cell therapy for Parkinson's disease: problems and prospects.
(
- Contribution to journal › Article
-
Mark
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
(
- Contribution to journal › Article
- 2004
-
Mark
Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.
(
- Contribution to journal › Article
-
Mark
Localized striatal delivery of GDNF as a treatment for Parkinson disease.
(
- Contribution to journal › Article
-
Mark
Special Issue Stem Cells - Preface
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.
2004) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 24(31). p.6958-6967(
- Contribution to journal › Article
-
Mark
Cell Therapy in Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Cell replacement therapy : helping the brain to repair itself
(
- Contribution to journal › Debate/Note/Editorial
- 2003
-
Mark
Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions.
(
- Contribution to journal › Article
-
Mark
Nigrostriatal {alpha}-synucleinopathy induced by viral vector-mediated overexpression of human {alpha}-synuclein: A new primate model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Neural transplantation for the treatment of Parkinson's disease
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Modeling CNS neurodegeneration by overexpression of disease-causing proteins using viral vectors.
(
- Contribution to journal › Scientific review
-
Mark
Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro.
(
- Contribution to journal › Article
-
Mark
Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model.
(
- Contribution to journal › Article
- 2002
-
Mark
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system
(
- Contribution to journal › Article
-
Mark
Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon.
(
- Contribution to journal › Article
-
Mark
Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry.
(
- Contribution to journal › Article
-
Mark
L-DOPA-Induced Dyskinesia in the Intrastriatal 6-Hydroxydopamine Model of Parkinson's Disease: Relation to Motor and Cellular Parameters of Nigrostriatal Function.
(
- Contribution to journal › Article
-
Mark
Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
(
- Contribution to journal › Article
-
Mark
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.
(
- Contribution to journal › Article
-
Mark
Evaluation of Tet-on system to avoid transgene downregulation in ex vivo gene transfer to the CNS
(
- Contribution to journal › Article
-
Mark
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector.
(
- Contribution to journal › Article
-
Mark
Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with long-distance axonal projections.
(
- Contribution to journal › Article
-
Mark
Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain.
(
- Contribution to journal › Article
-
Mark
Dyskinesias following neural transplantation in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Differentiation of the RN33B Cell Line into Forebrain Projection Neurons after Transplantation into the Neonatal Rat Brain.
(
- Contribution to journal › Article
- 2001
-
Mark
Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury
(
- Contribution to journal › Article
-
Mark
Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration
2001) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 21(8). p.2889-2896(
- Contribution to journal › Article
-
Mark
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease
(
- Contribution to journal › Article
- 2000
-
Mark
Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
(
- Contribution to journal › Article
-
Mark
Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model
(
- Contribution to journal › Article
-
Mark
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
(
- Contribution to journal › Article
-
Mark
Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement
(
- Contribution to journal › Article
-
Mark
EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum
(
- Contribution to journal › Article
-
Mark
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
(
- Contribution to journal › Article
-
Mark
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
(
- Contribution to journal › Article
-
Mark
Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson's disease
(
- Contribution to journal › Article
- 1999
-
Mark
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
(
- Contribution to journal › Article
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Mark
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
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- Contribution to journal › Article
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Mark
Sequential bilateral transplantation in Parkinson's disease: effects of the second graft
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- Contribution to journal › Article
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Mark
Neurturin enhances the survival of intrastriatal fetal dopaminergic transplants
(
- Contribution to journal › Article
- 1998
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Mark
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
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- Contribution to journal › Article
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Mark
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
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- Contribution to journal › Article
- 1997
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Mark
Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
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- Contribution to journal › Article
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Mark
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
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- Contribution to journal › Scientific review
- 1996
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Mark
Extensive reinnervation of the hippocampus by embryonic basal forebrain cholinergic neurons grafted into the septum of neonatal rats with selective cholinergic lesions
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- Contribution to journal › Article
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Mark
Effects of neonatal lesions of the basal forebrain cholinergic system by 192 immunoglobulin G-saporin : biochemical, behavioural and morphological characterization
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- Contribution to journal › Article
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Mark
Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in rats
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- Contribution to journal › Article
- 1995
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Mark
Preservation of fetal ventral mesencephalic cells by cool storage : in-vitro viability and TH-positive neuron survival after microtransplantation to the striatum
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- Contribution to journal › Article
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Mark
Selective lesioning of the basal forebrain cholinergic system by intraventricular 192 IgG-saporin : behavioural, biochemical and stereological studies in the rat
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- Contribution to journal › Article
- 1994
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Mark
Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocampus by superior cervical ganglion or fetal locus coeruleus grafts
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- Contribution to journal › Article
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Mark
Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease
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- Contribution to journal › Article
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Mark
A microtransplantation approach for cell suspension grafting in the rat Parkinson model : a detailed account of the methodology
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- Contribution to journal › Article
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Mark
Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocmapus by superior cervical ganglion or fetal locus coeruleus grafts
(
- Contribution to journal › Article
- 1993
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Mark
Sequential intrastriatal grafting of allogeneic embryonic dopamine-rich neuronal tissue in adult rats : will the second graft be rejected?
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- Contribution to journal › Article
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Mark
Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism
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- Contribution to journal › Article
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Mark
Basal forebrain grafts in the hippocampus and neocortex : regulation of acetylcholine release
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- Contribution to journal › Article
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Mark
Functional activity of intrahippocampal septal grafts is regulated by catecholaminergic host afferents as studied by microdialysis of acetylcholine
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- Contribution to journal › Article
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Mark
Characterization of in vivo noradrenaline release from superior cervical ganglia or fetal locus coeruleus transplanted to the subcortically deafferented hippocampus in the rat
(
- Contribution to journal › Article
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Mark
Compensatory changes of in vivo acetylcholine and noradrenaline release in the hippocampus after partial deafferentation, as monitored by microdialysis
(
- Contribution to journal › Article
- 1992
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Mark
Striatal c-fos Induction by Cocaine or Apomorphine Occurs Preferentially in Output Neurons Projecting to the Substantia Nigra in the Rat
(
- Contribution to journal › Article
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Mark
Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
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- Contribution to journal › Article
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Mark
Transplantation of fetal dopamine neurons in Parkinson's disease : PET [18F]6-L-fluorodopa studies in two patients with putaminal implants
(
- Contribution to journal › Article
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Mark
Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system
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- Contribution to journal › Article
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Mark
Acetylcholine release in the hippocampus : regulation by monoaminergic afferents as assessed by in vivo microdialysis
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- Contribution to journal › Article
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Mark
Behaviour-dependent changes in acetylcholine release in normal and graft-reinnervated hippocampus : evidence for host regulation of grafted cholinergic neurons
(
- Contribution to journal › Article
- 1991
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Mark
Host Brain Regulation of Fetal Locus Coeruleus Neurons Grafted to the Hippocampus in 6-Hydroxydopamine-Treated Rats. An Intracerebral Microdialysis Study
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- Contribution to journal › Article
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Mark
Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease
(
- Contribution to journal › Article
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Mark
In vivo acetylcholine release as measured by microdialysis is unaltered in the hippocampus of cognitively impaired aged rats with degenerative changes in the basal forebrain
(
- Contribution to journal › Article
- 1990
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Mark
The Importance of Graft Placement and Task Complexity for Transplant-Induced Recovery of Simple and Complex Sensorimotor Deficits in Dopamine Denervated Rats
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- Contribution to journal › Article
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Mark
Editorial note
(
- Contribution to journal › Article
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Mark
Chapter 83 Neural transplantation in Parkinson's disease : the Swedish experience
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- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
In reply : Fetal brain grafts and Parkinson's disease
(
- Contribution to journal › Letter
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Mark
Amelioration of spatial memory impairment by intrahippocampal grafts of mixed septal and raphe tissue in rats with combined cholinergic and serotonergic denervation of the forebrain
(
- Contribution to journal › Article
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Mark
Acetylcholine release from intrahippocampal septal grafts is under control of the host brain
1990) In Proceedings of the National Academy of Sciences of the United States of America 87(7). p.51-2647(
- Contribution to journal › Article
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Mark
Synaptic connections formed by grafts of different types of cholinergic neurons in the host hippocampus
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- Contribution to journal › Article
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Mark
Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioural activation
(
- Contribution to journal › Article
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Mark
Reafferentation of the subcortically denervated hippocampus as a model for transplant-induced functional recovery in the CNS
(
- Contribution to journal › Scientific review
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Mark
Intracerebral microdialysis as a tool to monitor transmitter release from grafted cholinergic and monoaminergic neurons
(
- Contribution to journal › Article
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Mark
Acetylcholine release from intrahippocampal septal grafts is under control by the host brain : a microdialysis study
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 1989
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Mark
Transplantation strategies in the treatment of Parkinson's disease : experimental basis and clinical trials
(
- Contribution to journal › Article
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Mark
Hippocampal Noradrenaline and Serotonin Release over 24 Hours as Measured by the Dialysis Technique in Freely Moving Rats : Correlation to Behavioural Activity State, Effect of Handling and Tail-Pinch
(
- Contribution to journal › Article
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Mark
Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats
(
- Contribution to journal › Article
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Mark
Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up
(
- Contribution to journal › Article
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Mark
Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice
(
- Contribution to journal › Article
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Mark
Intracerebral xenografts of dopamine neurons : the role of immunosuppression and the blood-brain barrier
(
- Contribution to journal › Article
- 1988
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Mark
Fetal dopamine-rich mesencephalic grafts in Parkinson's disease
(
- Contribution to journal › Letter
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Mark
Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern
(
- Contribution to journal › Article
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Mark
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease : immunological aspects, spontaneous and drug-induced behaviour, and dopamine release
(
- Contribution to journal › Article
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Mark
Immunological aspects of neural grafting in the mammalian central nervous system
(
- Contribution to journal › Article
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Mark
Can human fetal dopamine neuron grafts provide a therapy for Parkinson's disease?
(
- Contribution to journal › Scientific review
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Mark
Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat
(
- Contribution to journal › Article
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Mark
Comparison of growth and reinnervation properties of cholinergic neurons from different brain regions grafted to the hippocampus
(
- Contribution to journal › Article
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Mark
Electrophysiological and pharmacological properties of neurons within solid basal forebrain transplants in the rat brain
(
- Contribution to journal › Article
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Mark
Human fetal dopamine neurons grafted in a rat model of Parkinson's disease : ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry
(
- Contribution to journal › Article
- 1987
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Mark
Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion
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- Contribution to journal › Article
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Mark
Intracerebral grafting of dopamine neurons. Experimental basis for clinical trials in patients with Parkinson's disease
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- Contribution to journal › Article
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Mark
Spatial learning and memory following fimbria-fornix transection and grafting of fetal septal neurons to the hippocampus
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- Contribution to journal › Article
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Mark
Synaptogenesis of grafted cholinergic neurons
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- Contribution to journal › Article
- 1986
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Mark
Grafted septal neurons form cholinergic synaptic connections in the dentate gyrus of behaviorally impaired aged rats
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- Contribution to journal › Article
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Mark
Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease
(
- Contribution to journal › Article
- 1985
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Mark
Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons
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- Contribution to journal › Article
- 1983
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Mark
Intracerebral grafting of neuronal cell suspensions. III. Activaty of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism
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- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. VIII. Cell survival and axonal outgrcwth of dcpaminergic and cholinergic cells in the aged brain.
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- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cells implanted in different brain sites
(
- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. V. Behavioural recovery in rats with bilateral 6-OHDA lesions following implantation of nigral cell suspensions.
(
- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation.
(
- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. VI. Survival and growth of intrahippocampal implants of septal cell suspensions
(
- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. VII. Recovery of choline acetyltransferase activity and acetylcholine synthesis in the denervated hippccampus reinnervated by septal suspension implants
(
- Contribution to journal › Article
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Mark
Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral implants of nigral cell suspensions in different forebrain sites
(
- Contribution to journal › Article