Developmental and Regenerative Neurobiology
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- 2024
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Mark
Modular 3D printed platform for fluidically connected human brain organoid culture
(
- Contribution to journal › Article
-
Mark
Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons
(
- Contribution to journal › Article
-
Mark
The history and status of dopamine cell therapies for Parkinson's disease
2024) In BioEssays(
- Contribution to journal › Scientific review
-
Mark
The AAV-α-Synuclein Model of Parkinson's Disease : An Update
2024) In Journal of Parkinson's Disease(
- Contribution to journal › Scientific review
-
Mark
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Expanding the therapeutic potential of neuro(active)steroids : a promising strategy for hyperdopaminergic behavioral phenotypes
(
- Contribution to journal › Scientific review
- 2023
-
Mark
Cell Replacement Therapy for Parkinson's Disease - Evaluating the potential of autologous grafting.
2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Restorative cell and gene therapies for Parkinson's disease
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants
in vivo.
(
- Contribution to journal › Article
-
Mark
Protocol for optical clearing and imaging of fluorescently labeled ex vivo rat brain slices
(
- Contribution to journal › Article
-
Mark
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling
(
- Contribution to journal › Article
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Mark
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
(
- Contribution to journal › Article
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Mark
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
(
- Contribution to journal › Article
-
Mark
Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
(
- Contribution to journal › Article
-
Mark
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
(
- Contribution to journal › Article
-
Mark
LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
(
- Contribution to journal › Article
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Mark
In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids
(
- Contribution to journal › Article
-
Mark
Athymic Nude Rat Brain Atlas
2023)(
- Book/Report › Book
-
Mark
hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum
(
- Contribution to journal › Article
- 2022
-
Mark
Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia
(
- Contribution to journal › Article
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Mark
Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery
(
- Contribution to journal › Article
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Mark
A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
(
- Contribution to journal › Article
-
Mark
Islet Gene View-a tool to facilitate islet research
(
- Contribution to journal › Article
-
Mark
Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs
(
- Contribution to journal › Article
-
Mark
Targets for astrocyte-based treatments of Parkinson's disease (PD)
(
- Contribution to journal › Article
-
Mark
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease
(
- Contribution to journal › Article
-
Mark
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
(
- Contribution to journal › Article
-
Mark
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
(
- Contribution to journal › Scientific review
-
Mark
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells
(
- Contribution to journal › Article
-
Mark
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
(
- Contribution to journal › Article
-
Mark
Silk scaffolding drives self-assembly of functional and mature human brain organoids
(
- Contribution to journal › Article
-
Mark
Emerging strategies in 3D printed tissue models for in vitro biomedical research
2022) p.207-246(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
(
- Contribution to journal › Article
-
Mark
Exploring Direct Conversion of Human Glia into Therapeutic Neurons
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
- 2021
-
Mark
Dopamine Cell Therapy : From Cell Replacement to Circuitry Repair
(
- Contribution to journal › Scientific review
-
Mark
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons
(
- Contribution to journal › Article
-
Mark
Reprogramming Stars #4 : A Reprogramming Approach for Parkinson's Disease-An Interview with Dr. Malin Parmar
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
(
- Contribution to journal › Article
-
Mark
Repairing the Parkinson Brain
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Exploring Patient-Specific Cell Replacement Therapy for Parkinson's Disease
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation
(
- Contribution to journal › Article
-
Mark
Dopamine Neuron Diversity : Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing
(
- Contribution to journal › Scientific review
-
Mark
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
(
- Contribution to journal › Scientific review
-
Mark
Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?
(
- Contribution to journal › Article
-
Mark
GDNF Therapy : Can We Make It Work?
(
- Contribution to journal › Article
-
Mark
Neural tube patterning : from a minimal model for rostrocaudal patterning toward an integrated 3D model
(
- Contribution to journal › Article
-
Mark
Activation of endogenous retroviruses during brain development causes an inflammatory response
(
- Contribution to journal › Article
-
Mark
3D biomaterial models of human brain disease
(
- Contribution to journal › Article
- 2020
-
Mark
Parkinson’s disease laterality : a 11C-PE2I PET imaging study
2020) In Journal of Neurology(
- Contribution to journal › Article
-
Mark
BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia
(
- Contribution to journal › Article
-
Mark
Animal Models of Parkinson's Disease : Are They Useful or Not?
(
- Contribution to journal › Scientific review
-
Mark
Long Non-coding RNA T-UCstem1 Controls Progenitor Proliferation and Neurogenesis in the Postnatal Mouse Olfactory Bulb through Interaction with miR-9
(
- Contribution to journal › Article
-
Mark
3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices
(
- Contribution to journal › Article
-
Mark
GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop
(
- Contribution to journal › Article
-
Mark
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair : 40 Years in Perspective
(
- Contribution to journal › Scientific review
-
Mark
Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(16). p.9094-9100(
- Contribution to journal › Article
-
Mark
Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons
(
- Contribution to journal › Article
-
Mark
Functional and Transcriptional Studies of Human Dopaminergic Neurons
2020) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits
(
- Contribution to journal › Article
-
Mark
The future of stem cell therapies for Parkinson disease
(
- Contribution to journal › Scientific review
-
Mark
Preface : The evolving scenario of Parkinson's research
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
From Skin to Brain : A Parkinson's Disease Patient Transplanted with His Own Cells
(
- Contribution to journal › Article
-
Mark
Light sheet fluorescence microscopy of optically cleared brains for studying the glymphatic system
(
- Contribution to journal › Article
-
Mark
Animal models for preclinical Parkinson´s research: An update and critical appraisal
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease
(
- Contribution to journal › Article
-
Mark
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(26). p.15209-15220(
- Contribution to journal › Article
-
Mark
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
(
- Contribution to journal › Article
-
Mark
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells
(
- Contribution to journal › Article
-
Mark
Directing and Dissecting the Fate of Dopaminergic Neurons - Multiple Avenues towards Cell Replacement Therapy in Parkinson's Disease
2020) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (monograph)
-
Mark
Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons
(
- Contribution to journal › Article
- 2019
-
Mark
Stem cell culture conditions and stability : a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform
(
- Contribution to journal › Article
-
Mark
Long non-coding RNA in stem cell pluripotency and lineage commitment : functions and evolutionary conservation
(
- Contribution to journal › Article
-
Mark
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development
(
- Contribution to journal › Article
-
Mark
The amphetamine induced rotation test : A re-assessment of its use as a tool to monitor motor impairment and functional recovery in rodent models of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force
(
- Contribution to journal › Article
-
Mark
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons
(
- Contribution to journal › Article
-
Mark
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors
2019) In Journal of visualized experiments : JoVE(
- Contribution to journal › Article
-
Mark
Botulinum and tetanus neurotoxins
(
- Contribution to journal › Scientific review
-
Mark
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes
(
- Contribution to journal › Article
-
Mark
Direct reprogramming into interneurons : potential for brain repair
(
- Contribution to journal › Scientific review
-
Mark
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Research Collaborations: A guide for early career researchers by early career researchers
2019) In The League of European Research Universities (LERU)(
- Book/Report › Report
-
Mark
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
2019) In Proceedings of the National Academy of Sciences of the United States of America 116(52). p.27053-27062(
- Contribution to journal › Article
- 2018
-
Mark
Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
(
- Contribution to journal › Article
-
Mark
In vivo electrochemical studies of optogenetic control of glutamate signaling measured using enzyme-based ceramic microelectrode arrays
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Dermal fibroblasts from patients with Parkinson's disease have normal GCase activity and autophagy compared to patients with PD and GBA mutations
(
- Contribution to journal › Article
-
Mark
Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts
(
- Contribution to journal › Article
-
Mark
Towards stem cell based therapies for parkinson’s disease
(
- Contribution to journal › Article
-
Mark
New approaches for brain repair-from rescue to reprogramming
(
- Contribution to journal › Scientific review
-
Mark
Repairing the brain : Cell replacement using stem cell-based technologies
(
- Contribution to journal › Scientific review
-
Mark
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
(
- Contribution to journal › Article
-
Mark
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
(
- Contribution to journal › Article
-
Mark
The serotonergic system in L-DOPA-induced dyskinesia : pre-clinical evidence and clinical perspective
(
- Contribution to journal › Article
-
Mark
Cell Replacement Therapy for Parkinson's Disease: Potential for Circuitry Repair
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
(
- Contribution to journal › Article