Diabetes - Epigenetics
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- 2024
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Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS
(
- Contribution to journal › Article
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Mark
The Impact of Our Lifestyle on the Epigenome and Metabolism
2024) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Monitoring the Intracellular Fate of Molecular Beacons : The Challenge of False Positive Signals
2024) In Advanced NanoBiomed Research(
- Contribution to journal › Article
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Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets
(
- Contribution to journal › Article
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MicroRNA 29 modulates β-cell mitochondrial metabolism and insulin secretion via underlying miR-29-OXPHOS complex pathways
(
- Contribution to journal › Article
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Achieving efficient clonal beta cells transfection using nanostraw/nanopore-assisted electroporation
(
- Contribution to journal › Article
- 2023
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Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells
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- Contribution to journal › Article
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Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
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- Contribution to journal › Article
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Liver saturated fat content associates with hepatic DNA methylation in obese individuals
(
- Contribution to journal › Article
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Salt-inducible kinases are required for glucose uptake and insulin signaling in human adipocytes
(
- Contribution to journal › Article
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Circulating triglycerides are associated with human adipose tissue DNA methylation of genes linked to metabolic disease
(
- Contribution to journal › Article
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Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics
(
- Contribution to journal › Article
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Effect of a 3-year lifestyle intervention on telomere length in participants from PREDIMED-Plus : A randomized trial
(
- Contribution to journal › Article
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Epigenetics and Obesity
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes
(
- Contribution to journal › Article
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DNA methylation partially mediates antidiabetic effects of metformin on HbA1c levels in individuals with type 2 diabetes
(
- Contribution to journal › Article
- 2022
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Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns, Which Associate With Future Diabetic Complications
(
- Contribution to journal › Article
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Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?
(
- Contribution to journal › Scientific review
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Mark
The highly expressed calcium-insensitive synaptotagmin-11 and synaptotagmin-13 modulate insulin secretion
(
- Contribution to journal › Article
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Type 2 diabetes classification : a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
(
- Contribution to journal › Article
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Pharmacoepigenetics in type 2 diabetes : is it clinically relevant?
(
- Contribution to journal › Debate/Note/Editorial
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Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
(
- Contribution to journal › Article
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Increased risk of Graves´ophthalmopathy in patients with increasing TRAb after radioiodine treatment and the impact of CTLA4 on TRAb titres
(
- Contribution to journal › Article
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Ex vivo and in vivo experimental investigation of miR-148a-3p as a novel therapy for insulin secretion and type 2 diabetes
2022) EASD, European Association for the Study of Diabetes, 58th annual meeting, In Diabetologia 65(Suppl 1).(
- Contribution to journal › Published meeting abstract
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Mark
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
(
- Contribution to journal › Article
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Mark
Epigenetic epidemiology and alterations in type 2 diabetes and obesity
2022) p.445-474(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Glucocorticoids and glucolipotoxicity alter the DNA methylome and function of human EndoC-βH1 cells
(
- Contribution to journal › Article
- 2021
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Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation, Which Associates With Body Composition in the Offspring
(
- Contribution to journal › Article
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Excess of glucocorticoids during late gestation impairs the recovery of offspring’s β-cell function after a postnatal injury
(
- Contribution to journal › Article
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Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids
(
- Contribution to journal › Article
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Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes : Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S
(
- Contribution to journal › Article
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Novel miR-29 mitochondrial-associated gene pathways predicted to regulate beta cell insulin secretion
2021) European Association for the Study of Diabetes (EASD) 57th Annual meeting In Diabetologia 64(Suppl 1).(
- Contribution to journal › Published meeting abstract
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Mark
Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes
(
- Contribution to journal › Article
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VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
(
- Contribution to journal › Article
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Statin therapy is associated with epigenetic modifications in individuals with Type 2 diabetes
(
- Contribution to journal › Article
- 2020
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Mark
Epigenome- and Transcriptome-wide Changes in Muscle Stem Cells from Low Birth Weight Men
(
- Contribution to journal › Article
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Epigenetic changes in islets of langerhans preceding the onset of diabetes
(
- Contribution to journal › Article
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Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes
(
- Contribution to journal › Article
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No symphony without bassoon and piccolo : Changes in synaptic active zone proteins in Huntington's disease
(
- Contribution to journal › Article
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Epigenetic regulation of insulin action and secretion – role in the pathogenesis of type 2 diabetes
(
- Contribution to journal › Scientific review
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Mark
Electroacupuncture mimics exercise-induced changes in skeletal muscle gene expression in women with polycystic ovary syndrome
(
- Contribution to journal › Article
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Mediterranean Diet and Telomere Length : A Systematic Review and Meta-Analysis
(
- Contribution to journal › Scientific review
- 2019
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Mark
Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
(
- Contribution to journal › Article
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Liver DNA methylation of FADS2 associates with FADS2 genotypex 06 Biological Sciences 0604 Genetics
(
- Contribution to journal › Article
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Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
(
- Contribution to journal › Article
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The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis
(
- Contribution to journal › Article
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Fasting unmasks differential fat and muscle transcriptional regulation of metabolic gene sets in low versus normal birth weight men
(
- Contribution to journal › Article
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ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.
(
- Contribution to journal › Article
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Low-Dose Oral Ketamine for Procedural Analgesia in Pediatric Cancer Patients Undergoing Lumbar Puncture at a Resource-Limited Cancer Hospital in India
(
- Contribution to journal › Article
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Mark
Epigenetics in Human Obesity and Type 2 Diabetes
(
- Contribution to journal › Scientific review
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Mark
Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets
(
- Contribution to journal › Article
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Epigenome-wide association study of incident type 2 diabetes in a British population : EPIC-Norfolk study
(
- Contribution to journal › Article
- 2018
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Mark
DNA methylation in the pathogenesis of type 2 diabetes in humans
(
- Contribution to journal › Scientific review
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Mark
Serum and gene expression levels of CT-1, IL-6, and TNF-α after a lifestyle intervention in obese children
(
- Contribution to journal › Article
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A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary Syndrome
(
- Contribution to journal › Article
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The effects of high glucose exposure on global gene expression and DNA methylation in human pancreatic islets
(
- Contribution to journal › Article
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Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
(
- Contribution to journal › Article
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Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children
(
- Contribution to journal › Article
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MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation
(
- Contribution to journal › Article
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Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels
(
- Contribution to journal › Article
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Mark
DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary Syndrome
(
- Contribution to journal › Article
- 2017
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Mark
HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
(
- Contribution to journal › Article
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Hepatic DPP4 DNA methylation associates with fatty liver
(
- Contribution to journal › Article
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Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver
(
- Contribution to journal › Article
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Serum oxidized low-density lipoprotein levels are related to cardiometabolic risk and decreased after a weight loss treatment in obese children and adolescents
(
- Contribution to journal › Article
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Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
(
- Contribution to journal › Article
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Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver
(
- Contribution to journal › Article
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DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes
(
- Contribution to journal › Scientific review
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Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity
(
- Contribution to journal › Article
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Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue : A randomized controlled trial
(
- Contribution to journal › Article
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36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner
(
- Contribution to journal › Article
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Fetal hyperglycemia changes human preadipocyte function in adult life
(
- Contribution to journal › Article
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Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
(
- Contribution to journal › Article
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Role of dietary pattern and obesity on telomere homeostasis
2017) p.133-148(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2016
-
Mark
The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes
(
- Thesis › Doctoral thesis (compilation)
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Mark
NIH working group report-using genomic information to guide weight management: From universal to precision treatment.
(
- Contribution to journal › Scientific review
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Mark
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
(
- Contribution to journal › Article
-
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Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
(
- Contribution to journal › Article
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Developmental programming : State-of-the-science and future directions: Summary from a Pennington Biomedical symposium
(
- Contribution to journal › Scientific review
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Epigenetic markers to further understand insulin resistance
(
- Contribution to journal › Debate/Note/Editorial
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Epigenetic programming of adipose-derived stem cells in low birthweight individuals
(
- Contribution to journal › Article
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Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome
(
- Contribution to journal › Article
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Mark
Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes
(
- Contribution to journal › Article
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DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk
(
- Contribution to journal › Article
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Genome-wide analysis of the DNA methylation landscape in human tissues
2016)(
- Thesis › Doctoral thesis (compilation)
-
Mark
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
(
- Contribution to journal › Article
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Risk för typ 2-diabetes kunde förutspås med epigenetik
(
- Contribution to journal › Debate/Note/Editorial
- 2015
-
Mark
Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
(
- Contribution to journal › Article
-
Mark
The potential use of DNA methylation biomarkers to identify risk and progression of type 2 diabetes.
(
- Contribution to journal › Scientific review
-
Mark
Study of DNA methylation in human pancreatic islets
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?
(
- Contribution to journal › Scientific review
-
Mark
Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.
(
- Contribution to journal › Article
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Mark
Helsinki alert of biodiversity and health
(
- Contribution to journal › Scientific review
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Mark
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
(
- Contribution to journal › Article
-
Mark
Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.
(
- Contribution to journal › Article
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Mark
DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes.
(
- Contribution to journal › Scientific review
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Mark
Less pronounced response to exercise in healthy relatives to type 2 diabetics compared to controls.
(
- Contribution to journal › Article
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Mark
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
(
- Contribution to journal › Article
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Mark
lobChIP: from cells to sequencing ready ChIP libraries in a single day.
(
- Contribution to journal › Article
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Mark
Genome-Wide DNA and Histone Modification Studies in Metabolic Disease
2015) p.255-270(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2014
-
Mark
Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment.
(
- Contribution to journal › Article
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Mark
Epigenetic adaptation to regular exercise in humans.
(
- Contribution to journal › Scientific review
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Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
(
- Contribution to journal › Article
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Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding
(
- Contribution to journal › Article
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Mark
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
(
- Contribution to journal › Article
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Mark
Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
(
- Contribution to journal › Article
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Mark
Genetic, non-genetic and epigenetic risk determinants in developmental programming of type 2 diabetes.
(
- Contribution to journal › Scientific review
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Mark
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms.
(
- Contribution to journal › Article
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β-cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment.
(
- Contribution to journal › Article
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Mark
Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.
(
- Contribution to journal › Article
- 2013
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Mark
DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?
(
- Contribution to journal › Article
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Mark
Effect of exercise on DNA methylation and metabolism in human adipose tissue and skeletal muscle.
(
- Contribution to journal › Debate/Note/Editorial
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Mark
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.
(
- Contribution to journal › Article
-
Mark
Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
Coordinate changes in histone modifications, mRNA levels and metabolite profiles in clonal INS-1 832/13 β-cells accompany functional adaptations to lipotoxicity.
(
- Contribution to journal › Article
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Mark
Osteocalcin, glucose metabolism, lipid profile and chronic low-grade inflammation in middle-aged and elderly Chinese.
(
- Contribution to journal › Article
- 2012
-
Mark
Genetic and epigenetic influence on oxidative phosphorylation, islet function and type 2 diabetes in humans
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Regulation of core clock genes in human islets.
(
- Contribution to journal › Article
-
Mark
Search for molecular and metabolic mechanisms contributing to impaired β-cell function
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle.
(
- Contribution to journal › Article
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Mark
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-aged and older Chinese population
(
- Contribution to journal › Article
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Mark
Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.
2012) In Diabetes(
- Contribution to journal › Article
-
Mark
Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
(
- Contribution to journal › Article
- 2011
-
Mark
Prevalence of non-alcoholic fatty liver disease and its relation to hypoadiponectinaemia in the middle-aged and elderly Chinese population
(
- Contribution to journal › Article
-
Mark
Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects.
(
- Contribution to journal › Article
-
Mark
Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
- 2010
-
Mark
Oxidative phosphorylation-dependent insulin secretion in pancreatic beta cells: new insights by disrupting TFB1M
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.491-491(
- Contribution to journal › Published meeting abstract
- 2009
-
Mark
Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.
(
- Contribution to journal › Article
- 2008
-
Mark
PGC-1 alpha and PGC-1 beta are related to markers for fibre type composition in human skeletal muscle
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(S1). p.130-130(
- Contribution to journal › Published meeting abstract
-
Mark
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.
(
- Contribution to journal › Article
- 2007
-
Mark
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
(
- Contribution to journal › Article
- 2006
-
Mark
The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects.
(
- Contribution to journal › Article
-
Mark
Variation in the adiponutrin gene influences its expression and associates with obesity.
(
- Contribution to journal › Article
- 2005
-
Mark
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
(
- Contribution to journal › Article
-
Mark
Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue
(
- Contribution to journal › Article
-
Mark
FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes
2005)(
- Thesis › Doctoral thesis (compilation)
- 2004
-
Mark
Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.
(
- Contribution to journal › Article
-
Mark
The FOXC2 C-512T Polymorphism Is Associated with Obesity and Dyslipidemia.
(
- Contribution to journal › Article
- 2003
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Mark
Pro-opiomelanocortin gene is associated with serum leptin levels in lean but not in obese individuals.
(
- Contribution to journal › Article
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Mark
Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.
(
- Contribution to journal › Article
- 2002
-
Mark
FOXC2 mRNA Expression and a 5' Untranslated Region Polymorphism of the Gene Are Associated With Insulin Resistance.
(
- Contribution to journal › Article
- 1990
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Mark
Effects of sympathetic stimulation on C-fibre response after peripheral nerve compression : an experimental study in the rabbit common peroneal nerve
(
- Contribution to journal › Article