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- 2024
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Mark
Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration
(
- Contribution to journal › Article
- 2023
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Mark
The photoreceptor protective cGMP-analog Rp-8-Br-PET-cGMPS interacts with cGMP-interactors PKGI, PDE1, PDE6, and PKAI in the degenerating mouse retina
(
- Contribution to journal › Article
-
Mark
Pyruvate Kinase 2, an Energy Metabolism Related Enzyme, May Have a Neuroprotective Function in Retinal Degeneration
(
- Contribution to journal › Article
-
Mark
A Potential Neuroprotective Role for Pyruvate Kinase 2 in Retinal Degeneration
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
The Phosphoproteome of the Rd1 Mouse Retina, a Model of Inherited Photoreceptor Degeneration, Changes after Protein Kinase G Inhibition
(
- Contribution to journal › Article
- 2022
-
Mark
Enhanced cGMP Interactor Rap Guanine Exchange Factor 4 (EPAC2) Expression and Activity in Degenerating Photoreceptors: : A Neuroprotective Response?
(
- Contribution to journal › Article
-
Mark
A Potential Role of Cyclic Dependent Kinase 1 (CDK1) in Late Stage of Retinal Degeneration
(
- Contribution to journal › Article
-
Mark
The stereospecific interaction sites and target specificity of cGMP analogs in mouse cortex
(
- Contribution to journal › Article
- 2021
-
Mark
cGMP-PKG dependent transcriptome in normal and degenerating retinas: Novel insights into the retinitis pigmentosa pathology
(
- Contribution to journal › Article
-
Mark
The cGMP system in normal and degenerating mouse neuroretina : New proteins with cGMP interaction potential identified by a proteomics approach
(
- Contribution to journal › Article
- 2020
-
Mark
Cellular mechanisms of hereditary photoreceptor degeneration – Focus on cGMP
(
- Contribution to journal › Scientific review
- 2019
-
Mark
Drug delivery to retinal photoreceptors
(
- Contribution to journal › Scientific review
-
Mark
Modulation of Calcium Overload and Calpain Activity
(
- Contribution to journal › Article
-
Mark
Modulation of cGMP-signalling to Prevent Retinal Degeneration
(
- Contribution to journal › Article
- 2018
-
Mark
Electrospun nerve guide conduits have the potential to bridge peripheral nerve injuries in vivo.
(
- Contribution to journal › Article
-
Mark
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration
2018) In Proceedings of the National Academy of Sciences of the United States of America 115(13). p.2997-3006(
- Contribution to journal › Article
- 2016
-
Mark
Increased Plasma cGMP in a Family With Autosomal Recessive Retinitis Pigmentosa Due to Homozygous Mutations in the PDE6A Gene
(
- Contribution to journal › Article
-
Mark
Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations
(
- Contribution to journal › Article
-
Mark
G-CSF prevents caspase 3 activation in Schwann cells after sciatic nerve transection, but does not improve nerve regeneration
(
- Contribution to journal › Article
- 2014
-
Mark
Novel In Situ Activity Assays for the Quantitative Molecular Analysis of Neurodegenerative Processes in the Retina
(
- Contribution to journal › Article
-
Mark
Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors.
(
- Contribution to journal › Article
-
Mark
How Long Does a Photoreceptor Cell Take to Die? Implications for the Causative Cell Death Mechanisms
(
- Contribution to journal › Article
-
Mark
DNA methylation and differential gene regulation in photoreceptor cell death.
(
- Contribution to journal › Article
-
Mark
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration.
(
- Contribution to journal › Article
- 2013
-
Mark
Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms
(
- Contribution to journal › Article
-
Mark
Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins
(
- Contribution to journal › Article
-
Mark
Retinitis Pigmentosa: Over-expression of anti-ageing protein Klotho in degenerating photoreceptors.
2013) In Journal of Neurochemistry(
- Contribution to journal › Article
- 2011
-
Mark
Calpain and PARP Activation during Photoreceptor Cell Death in P23H and S334ter Rhodopsin Mutant Rats
(
- Contribution to journal › Article
- 2010
-
Mark
PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function
(
- Contribution to journal › Article
-
Mark
Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.
(
- Contribution to journal › Article
-
Mark
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse
(
- Contribution to journal › Article
-
Mark
Photoreceptor rescue and toxicity induced by different calpain inhibitors
(
- Contribution to journal › Article
-
Mark
Antioxidants rescue photoreceptors in rd1 mice: Relationship with thiol metabolism
(
- Contribution to journal › Article
-
Mark
Human neural progenitor cells promote photoreceptor survival in retinal explants.
(
- Contribution to journal › Article
- 2009
-
Mark
Study of Gene-Targeted Mouse Models of Splicing Factor Gene Prpf31 Implicated in Human Autosomal Dominant Retinitis Pigmentosa (RP)
(
- Contribution to journal › Article
-
Mark
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models
(
- Contribution to journal › Article
-
Mark
Serum-free retinal explant culture system and comparative rescue effects of LEDGF, GST, CNTF, BDNF, NGF, bFGF and antioxidants in the rd1 mouse model of retinitis pigmentosa
2009) p.263-299(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Physiopathology of retinal degeneration in rd1 mouse model of retinitis pigmentosa : TGF-Β1, proteinases and oxidative stress mechanisms
2009) p.1-41(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2008
-
Mark
Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach
(
- Contribution to journal › Article
-
Mark
Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration
(
- Contribution to journal › Scientific review
-
Mark
rd1 Mouse retina shows an imbalance in the activity of cysteine protease cathepsins and their endogenous inhibitor cystatin C.
(
- Contribution to journal › Article
- 2007
-
Mark
Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration.
(
- Contribution to journal › Article
-
Mark
CNTF plus BDNF treatment and neuroprotective pathways in the rd1 mouse retina
(
- Contribution to journal › Article
-
Mark
Calpain activity in retinal degeneration.
(
- Contribution to journal › Scientific review
-
Mark
Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.
(
- Contribution to journal › Article
- 2006
-
Mark
Differential modification of phosducin protein in degenerating rd1 ret is associated with constitutively active CaMKII in rod outer segments.
(
- Contribution to journal › Article
-
Mark
rd1 Mouse Retina Shows Imbalance in Cellular Distribution and Levels of TIMP-1/MMP-9, TIMP-2/MMP-2 and Sulfated Glycosaminoglycans.
(
- Contribution to journal › Article
-
Mark
Calpain is activated in degenerating photoreceptors in the rd1 mouse.
(
- Contribution to journal › Article
-
Mark
Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina.
(
- Contribution to journal › Article
- 2005
-
Mark
Decreased glutathione transferase levels in rd1/rd1 mouse retina: Replenishment protects photoreceptors in retinal explants.
(
- Contribution to journal › Article
-
Mark
Differential Akt activation in the photoreceptors of normal and rd1 mice.
(
- Contribution to journal › Article
- 2004
-
Mark
Glutathione S-transferase µ(GST) modifies activities of proteases and levels of cystatin C secreted by mouse retinal explants
(
- Contribution to journal › Published meeting abstract
- 2003
-
Mark
Involvement of alpha 7 beta 1 integrin in the conditioning-lesion effect on sensory axon regeneration
(
- Contribution to journal › Article
-
Mark
Role of phosphatidylinositol 3-kinase in neuronal survival and axonal outgrowth of adult mouse dorsal root ganglia explants.
(
- Contribution to journal › Article
- 2002
-
Mark
Mitogen-activated protein kinase inhibition reveals differences in signalling pathways activated by neurotrophin-3 and other growth-stimulating conditions of adult mouse dorsal root ganglia neurons.
(
- Contribution to journal › Article
- 2000
-
Mark
Leukemia inhibitory factor null mice : Unhampered in vitro outgrowth of sensory axons but reduced stimulatory potential by nerve segments
(
- Contribution to journal › Article
-
Mark
Axonal outgrowth from adult mouse nodose ganglia In vitro is stimulated by neurotrophin-4 in a Trk receptor and mitogen-activated protein kinase-dependent way
(
- Contribution to journal › Article
-
Mark
Mitogen activated protein kinase inhibition by PD98059 blocks nerve growth factor stimulated axonal outgrowth from adult mouse dorsal root ganglia in vitro
(
- Contribution to journal › Article
- 1999
-
Mark
Involvement of axonal phospholipase A2 activity in the outgrowth of adult mouse sensory axons in vitro
(
- Contribution to journal › Article
-
Mark
Protein kinase C inhibition has only a transient growth arresting effect on in vitro regenerating mouse sensory neurons
(
- Contribution to journal › Article
-
Mark
Upregulation of cytosolic phospholipase A2 correlates with apoptosis in mouse superior cervical and dorsal root ganglia neurons
(
- Contribution to journal › Article
- 1998
-
Mark
Use of explant cultures of peripheral nerves of adult vertebrates to study axonal regeneration in vitro
(
- Contribution to journal › Article
-
Mark
The immune modulator Linomide prevents neuronal death in injured peripheral nerves of the mouse
(
- Contribution to journal › Article
-
Mark
Mitogen activated protein (MAP) kinase activity is increased in adult mouse superior cervical ganglia during culturing
(
- Contribution to journal › Article
- 1997
-
Mark
Effects of glial cell line-derived neurotrophic factor on axonal growth and apoptosis in adult mammalian sensory neurons in vitro
(
- Contribution to journal › Article
- 1996
-
Mark
Phospholipase A2 activity is required for regeneration of sensory axons in cultured adult sciatic nerves
(
- Contribution to journal › Article
-
Mark
Axonal outgrowth and neuronal apoptosis in cultured adult mouse dorsal root ganglion preparations : Effects of neurotrophins, of inhibition of neurotrophin actions and of prior axotomy
(
- Contribution to journal › Article
-
Mark
Protein kinase C and mouse sciatic nerve regeneration
(
- Contribution to journal › Article
- 1995
-
Mark
Neurones and glial cells of the mouse sciatic nerve undergo apoptosis after injury in Vivo and in Vitro
(
- Contribution to journal › Article
-
Mark
Increased cyclic AMP in in vitro regenerating frog sciatic nerves inhibits Schwann cell proliferation bur has no effect on axonal outgrowth
(
- Contribution to journal › Article
-
Mark
Okadaic Acid and Cultured Frog Sciatic Nerves : Potent Inhibition of Axonal Regeneration in Spite of Unaffected Schwann Cell Proliferation and Ganglionic Protein Synthesis
(
- Contribution to journal › Article
-
Mark
Increased levels of mitogen activated protein kinase (MAP-K) detected in the injured adult mouse sciatic nerve
(
- Contribution to journal › Article
-
Mark
Calmodulin and In Vitro Regenerating Frog Sciatic Nerves : Release and Extracellular Effects
(
- Contribution to journal › Article
-
Mark
Moderate elevation of extracellular potassium transiently inhibits regeneration of sensory axons in cultured adult sciatic nerves
(
- Contribution to journal › Article
- 1994
-
Mark
Insulin and IGF-II, but not IGF-I, stimulate the in vitro regeneration of adult frog sciatic sensory axons
(
- Contribution to journal › Article
-
Mark
Regenerating peripheral nerves release a diffusable protein kinase
(
- Contribution to journal › Article
-
Mark
Regenerating Peripheral Axons Transport and Release Low‐Molecular‐Mass Materials In Vitro
(
- Contribution to journal › Article
-
Mark
Early regeneration in vitro of adult mouse sciatic axons is dependent on local protein synthesis but may not involve neurotrophins
(
- Contribution to journal › Article
- 1993
-
Mark
Effects of insulin and insulin-like growth factor-2 on the in vitro regeneration of the frog sciatic nerve
(
- Contribution to journal › Article
- 1992
-
Mark
Effects of protein kinase inhibitors on regeneration in vitro of adult frog sciatic sensory axons
(
- Contribution to journal › Article
-
Mark
Growth cones of regenerating adult sciatic sensory axons release axonally transported proteins
(
- Contribution to journal › Article
-
Mark
Adenosine inhibition of the regeneration in vitro of adult frog sciatic sensory axons
(
- Contribution to journal › Article
- 1991
-
Mark
A calmodulin inhibitor with high specificity compound 48/80, inhibits axonal transport in frog nerves without disruption of axonal microtubules
(
- Contribution to journal › Article
-
Mark
Insulin stimulates ganglionic protein synthesis and reduces thymidine incorporation in support cells of the in vitro regenerating adult frog sciatic sensory neurons
(
- Contribution to journal › Article
-
Mark
A Fast Axonally Transported Protein of the Frog Sciatic Sensory Axons Undergoes Similar Qualitative Changes During Regeneration In Vitro and In Vivo
(
- Contribution to journal › Article
- 1990
-
Mark
Impaired nerve regeneration in streptozotocin-diabetic rats is improved by treatment with gangliosides
(
- Contribution to journal › Article
-
Mark
Regeneration in vitro of the adult frog sciatic sensory axons
(
- Contribution to journal › Article
- 1989
-
Mark
Nerve regeneration and serum levels of insulin-like growth factor-I in rats with streptozotocin-induced insulin deficiency
(
- Contribution to journal › Article
-
Mark
Impaired nerve regeneration in streptozotocin-diabetic rats. Effects of treatment with an aldose reductase inhibitor
(
- Contribution to journal › Scientific review
- 1987
-
Mark
Calmodulin‐Binding Proteins Within the Slow Phase of Axonal Transport in the Rabbit Vagus Nerve Per Ekstrom and Martin Kanje
(
- Contribution to journal › Article
-
Mark
The effects of trifluoperazine on fast and slow axonal transport in the rabbit vagus nerve
(
- Contribution to journal › Article
-
Mark
The use of the regenerating frog sciatic nerve for pharmacological studies of orthograde and retrograde axonal transport
(
- Contribution to journal › Article
- 1986
-
Mark
The effect of gossypol on fast axonal transport and microtubule assembly
(
- Contribution to journal › Article
- 1985
-
Mark
Ca2+-activated protease activity in frog sciatic nerve : Characterization and effect on rapidly transported axonal proteins
(
- Contribution to journal › Article
-
Mark
Effect of Estramustine Phosphate on the Assembly of Isolated Bovine Brain Microtubules and Fast Axonal Transport in the Frog Sciatic Nerve
(
- Contribution to journal › Article
- 1984
-
Mark
Is protease activity involved in fast axonal transport?
(
- Contribution to journal › Article
-
Mark
Inhibition of Fast Axonal Transport by erythro‐9‐[3‐(2‐Hydroxynonyl)]Adenine
(
- Contribution to journal › Article
- 1982
-
Mark
Effects of phenothiazines and dibenzazepines on axonal transport and microtubule assembly in vitro
(
- Contribution to journal › Article
-
Mark
The role of Ca2+ in rapid axonal transport.
1982) p.294-300(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Divalent cations and fast axonal transport in chemically desheathed (triton X-treated) frog sciatic nerve
(
- Contribution to journal › Article